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TMEM141 transmembrane protein 141 [ Homo sapiens (human) ]

Gene ID: 85014, updated on 9-Jun-2025
Official Symbol
TMEM141provided by HGNC
Official Full Name
transmembrane protein 141provided by HGNC
Primary source
HGNC:HGNC:28211
See related
Ensembl:ENSG00000244187 AllianceGenome:HGNC:28211
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in mitochondrion. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Ubiquitous expression in prostate (RPKM 62.3), colon (RPKM 54.7) and 25 other tissues See more
Orthologs
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See TMEM141 in Genome Data Viewer
Location:
9q34.3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136791344..136793317)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (149024225..149026198)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139685796..139687769)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107987143 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139665256-139665756 Neighboring gene Sharpr-MPRA regulatory region 7361 Neighboring gene ATPase H+ transporting V1 subunit G1 pseudogene 3 Neighboring gene CRISPRi-validated cis-regulatory element chr9.4332 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20540 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139690211-139690712 Neighboring gene Sharpr-MPRA regulatory region 12102 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139693993-139694696 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20542 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139695381-139695908 Neighboring gene coiled-coil domain containing 183 Neighboring gene CCDC183 antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr9:139701344-139701939 and GRCh37_chr9:139701940-139702536 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20546 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20547 Neighboring gene iron-sulfur cluster assembly 1 homolog (S. cerevisiae) pseudogene Neighboring gene RAB, member RAS oncogene family like 6

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • MGC14141

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HTP PubMed 
Preferred Names
transmembrane protein 141

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032928.4NP_116317.1  transmembrane protein 141

    See identical proteins and their annotated locations for NP_116317.1

    Status: VALIDATED

    Source sequence(s)
    BC007834, BU740670, CB107060
    Consensus CDS
    CCDS7007.1
    UniProtKB/Swiss-Prot
    A6NIZ7, Q5T5R5, Q96I45
    Related
    ENSP00000290079.8, ENST00000290079.9
    Conserved Domains (1) summary
    pfam15110
    Location:696
    TMEM141; TMEM141 protein family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    136791344..136793317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    149024225..149026198
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)