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HPDL 4-hydroxyphenylpyruvate dioxygenase like [ Homo sapiens (human) ]

Gene ID: 84842, updated on 13-Mar-2020

Summary

Official Symbol
HPDLprovided by HGNC
Official Full Name
4-hydroxyphenylpyruvate dioxygenase likeprovided by HGNC
Primary source
HGNC:HGNC:28242
See related
Ensembl:ENSG00000186603
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GLOXD1; 4-HPPD-L
Orthologs

Genomic context

See HPDL in Genome Data Viewer
Location:
1p34.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (45326895..45328679)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (45792545..45794347)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene zinc finger SWIM-type containing 5 Neighboring gene Sharpr-MPRA regulatory region 10410 Neighboring gene uncharacterized LOC105378691 Neighboring gene long intergenic non-protein coding RNA 1144 Neighboring gene mutY DNA glycosylase Neighboring gene testis associated actin remodelling kinase 2 Neighboring gene target of EGR1, exonuclease Neighboring gene peptidylprolyl isomerase A pseudogene 36

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC15668

Gene Ontology Provided by GOA

Function Evidence Code Pubs
4-hydroxyphenylpyruvate dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
aromatic amino acid family metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
4-hydroxyphenylpyruvate dioxygenase-like protein
Names
glyoxalase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032756.3NP_116145.1  4-hydroxyphenylpyruvate dioxygenase-like protein

    See identical proteins and their annotated locations for NP_116145.1

    Status: VALIDATED

    Source sequence(s)
    AI808699, AL359540, BC007293, BQ069740
    Consensus CDS
    CCDS519.1
    UniProtKB/Swiss-Prot
    Q96IR7
    Related
    ENSP00000335060.3, ENST00000334815.5
    Conserved Domains (3) summary
    cd07250
    Location:158363
    HPPD_C_like; C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS)
    TIGR01263
    Location:10368
    4HPPD; 4-hydroxyphenylpyruvate dioxygenase
    cl14632
    Location:10148
    Glo_EDI_BRP_like; This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    45326895..45328679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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