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LINC00467 long intergenic non-protein coding RNA 467 [ Homo sapiens (human) ]

Gene ID: 84791, updated on 17-Sep-2024

Summary

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Official Symbol
LINC00467provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 467provided by HGNC
Primary source
HGNC:HGNC:28227
See related
Ensembl:ENSG00000153363 MIM:620079; AllianceGenome:HGNC:28227
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ASAP; C1orf97
Expression
Biased expression in testis (RPKM 117.7) and thyroid (RPKM 6.1) See more
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Genomic context

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See LINC00467 in Genome Data Viewer
Location:
1q32.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (211382755..211432535)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (210628363..210678151)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (211556097..211605877)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2483 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1784 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2484 Neighboring gene TNF receptor associated factor 5 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1785 Neighboring gene uncharacterized LOC124904504 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:211550792-211551568 Neighboring gene uncharacterized LOC107985259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2485 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:211571607-211572350 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:211573836-211574577 Neighboring gene sorting nexin 25 pseudogene 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:211612887-211613110 Neighboring gene actin related protein 2/3 complex subunit 3 pseudogene 2 Neighboring gene RD3 regulator of GUCY2D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LINC00467 mediates the 5-fluorouracil resistance in breast cancer cells. Li L, et al. In Vitro Cell Dev Biol Anim, 2024 Jan. PMID 38127229
  2. Silencing of LINC00467 inhibits cell proliferation in testicular germ cell tumors cells. Zhu F, et al. Biomol Biomed, 2023 Sep 4. PMID 37078359, Free PMC Article
  3. LINC00467 facilitates the proliferation, migration and invasion of glioma via promoting the expression of inositol hexakisphosphate kinase 2 by binding to miR-339-3p. Zhang Y, et al. Bioengineered, 2022 Feb. PMID 35156508, Free PMC Article
  4. LINC00467 Is Upregulated by DNA Copy Number Amplification and Hypomethylation and Shows ceRNA Potential in Lung Adenocarcinoma. Wang W, et al. Front Endocrinol (Lausanne), 2021. PMID 35095769, Free PMC Article
  5. The Rs12569232 SNP Association with Vogt-Koyanagi-Harada Disease and Behcet's Disease is Probably Mediated by Regulation of Linc00467 Expression. Wang Q, et al. Ocul Immunol Inflamm, 2021 Nov 17. PMID 32400232

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC00467 mediates the 5-fluorouracil resistance in breast cancer cells.
    Title: LINC00467 mediates the 5-fluorouracil resistance in breast cancer cells.
  2. LINC00467 enhanced the proliferative, migratory and invasive ability of breast cancer cells by targeting miR-18a/b-5p/MAPK4 axis.
    Title: LINC00467 enhanced the proliferative, migratory and invasive ability of breast cancer cells by targeting miR-18a/b-5p/MAPK4 axis.
  3. Silencing of LINC00467 inhibits cell proliferation in testicular germ cell tumors cells.
    Title: Silencing of LINC00467 inhibits cell proliferation in testicular germ cell tumors cells.
  4. LINC00467 facilitates the proliferation, migration and invasion of glioma via promoting the expression of inositol hexakisphosphate kinase 2 by binding to miR-339-3p.
    Title: LINC00467 facilitates the proliferation, migration and invasion of glioma via promoting the expression of inositol hexakisphosphate kinase 2 by binding to miR-339-3p.
  5. Downregulated Reprimo by LINC00467 participates in the growth and metastasis of gastric cancer.
    Title: Downregulated Reprimo by LINC00467 participates in the growth and metastasis of gastric cancer.
  6. LINC00467 Is Upregulated by DNA Copy Number Amplification and Hypomethylation and Shows ceRNA Potential in Lung Adenocarcinoma.
    Title: LINC00467 Is Upregulated by DNA Copy Number Amplification and Hypomethylation and Shows ceRNA Potential in Lung Adenocarcinoma.
  7. Overexpressed LINC00467 promotes the viability and proliferation yet inhibits apoptosis of gastric cancer cells via raising ITGB3 level.
    Title: Overexpressed LINC00467 promotes the viability and proliferation yet inhibits apoptosis of gastric cancer cells via raising ITGB3 level.
  8. Knockdown of LINC00467 contributed to Axitinib sensitivity in hepatocellular carcinoma through miR-509-3p/PDGFRA axis.
    Title: Knockdown of LINC00467 contributed to Axitinib sensitivity in hepatocellular carcinoma through miR-509-3p/PDGFRA axis.
  9. The Rs12569232 SNP Association with Vogt-Koyanagi-Harada Disease and Behcet's Disease is Probably Mediated by Regulation of Linc00467 Expression.
    Title: The Rs12569232 SNP Association with Vogt-Koyanagi-Harada Disease and Behcet's Disease is Probably Mediated by Regulation of Linc00467 Expression.
  10. Linc00467 promotion of gastric cancer development by directly regulating miR-7-5p expression and downstream epidermal growth factor receptor.
    Title: Linc00467 promotion of gastric cancer development by directly regulating miR-7-5p expression and downstream epidermal growth factor receptor.
Submit: New GeneRIF Correction See all GeneRIFs (28)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • ATP synthase-associated peptide

Clone Names

  • FLJ27347, FLJ27348, MGC14801

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_026761.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK130858, BC005997, BP197632
    Related
    ENST00000656082.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    211382755..211432535
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    210628363..210678151
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_032705.3: Suppressed sequence

    Description
    NM_032705.3: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Chemical Information
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