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ACTRT3 actin related protein T3 [ Homo sapiens (human) ]

Gene ID: 84517, updated on 5-Aug-2022

Summary

Official Symbol
ACTRT3provided by HGNC
Official Full Name
actin related protein T3provided by HGNC
Primary source
HGNC:HGNC:24022
See related
Ensembl:ENSG00000184378 MIM:608534; AllianceGenome:HGNC:24022
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARPM1; ARP-T3
Summary
Predicted to be located in male germ cell nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 21.9), kidney (RPKM 1.3) and 1 other tissue See more
Orthologs
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Genomic context

See ACTRT3 in Genome Data Viewer
Location:
3q26.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (169766921..169769561, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (172550873..172553662, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (169484709..169487349, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 637, pseudogene Neighboring gene telomerase RNA component (TERC) promoter Neighboring gene telomerase RNA component Neighboring gene Sharpr-MPRA regulatory region 7912 Neighboring gene tRNA-Val (anticodon AAC) 1-1 Neighboring gene myoneurin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
EBI GWAS Catalog
Identification of a melanoma susceptibility locus and somatic mutation in TET2.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC15664

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in male germ cell nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin-related protein T3
Names
actin-related protein M1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032487.5NP_115876.3  actin-related protein T3

    See identical proteins and their annotated locations for NP_115876.3

    Status: VALIDATED

    Source sequence(s)
    AB049117, AI811210, AK055346
    Consensus CDS
    CCDS3206.1
    UniProtKB/Swiss-Prot
    Q96NJ0, Q9BYD9
    Related
    ENSP00000333037.1, ENST00000330368.3
    Conserved Domains (2) summary
    smart00268
    Location:7372
    ACTIN; Actin
    cl17037
    Location:9372
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    169766921..169769561 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    172550873..172553662 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)