PPC4 phosphoenolpyruvate carboxylase 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PPC4
Official Full Name: phosphoenolpyruvate carboxylase 4
Primary source: TAIR:AT1G68750
Locus tag: AT1G68750
See related: Araport:AT1G68750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATPPC4; F14K14.14; F14K14_14; phosphoenolpyruvate carboxylase 4
Summary: Encodes one of four Arabidopsis phosphoenolpyruvate (PEP) carboxylase proteins. But, it is more similar to bacterial PEP carboxylase than plant PEP carboxylase. Efforts to express this enzyme and to demonstrate its enzymatic activity in E.coli failed.
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Genomic context

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Location:: chromosome: 1

Exon count:: 20

Sequence:: Chromosome: 1; NC_003070.9 (25822716..25828147, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_105548.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
NOT enables phosphoenolpyruvate carboxylase activity	IDA Inferred from Direct Assay more info	PubMed
enables phosphoenolpyruvate carboxylase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within tricarboxylic acid cycle	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: phosphoenolpyruvate carboxylase 4

NP_177043.2

phosphoenolpyruvate carboxylase 4 (PPC4); CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Phosphoenolpyruvate carboxylase, active site (InterPro:IPR018129), Phosphoenolpyruvate carboxylase (InterPro:IPR001449), Phosphoenolpyruvate carboxylase, C-terminal region (InterPro:IPR021135); BEST Arabidopsis thaliana protein match is: phosphoenolpyruvate carboxylase 1 (TAIR:AT1G53310.3); Has 9944 Blast hits to 6686 proteins in 1878 species: Archae - 54; Bacteria - 5038; Metazoa - 4; Fungi - 0; Plants - 1854; Viruses - 0; Other Eukaryotes - 2994 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

25822716..25828147 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_105548.5 → NP_177043.2 phosphoenolpyruvate carboxylase 4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_177043.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8GVE8, Q9CA39, Q9SX35

UniProtKB/TrEMBL

A0A178W7Q9, A0A5S9WT09, A0A654ENX1

Conserved Domains (1) summary

PRK00009
Location:19 → 1032

PRK00009; phosphoenolpyruvate carboxylase; Reviewed