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MON1A MON1 homolog A, secretory trafficking associated [ Homo sapiens (human) ]

Gene ID: 84315, updated on 14-Aug-2021

Summary

Official Symbol
MON1Aprovided by HGNC
Official Full Name
MON1 homolog A, secretory trafficking associatedprovided by HGNC
Primary source
HGNC:HGNC:28207
See related
Ensembl:ENSG00000164077 MIM:611464
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SAND1
Expression
Ubiquitous expression in duodenum (RPKM 6.4), testis (RPKM 5.1) and 25 other tissues See more
Orthologs
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Genomic context

See MON1A in Genome Data Viewer
Location:
3p21.31
Exon count:
8
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49908869..49929811, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (49946302..49967445, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene actin like 11, pseudogene Neighboring gene uncharacterized LOC102724438 Neighboring gene macrophage stimulating 1 receptor Neighboring gene RNA binding motif protein 6 Neighboring gene RBM5 antisense RNA 1 Neighboring gene RNA binding motif protein 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ97088, MGC13272

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting to vacuole IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Mon1-Ccz1 complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
vacuolar fusion protein MON1 homolog A
Names
MON1 secretory trafficking family member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142501.2NP_001135973.2  vacuolar fusion protein MON1 homolog A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a.
    Source sequence(s)
    AC105935
    Consensus CDS
    CCDS46830.1
    Related
    ENSP00000404793.2, ENST00000455683.6
    Conserved Domains (1) summary
    pfam03164
    Location:38392
    Mon1; Trafficking protein Mon1
  2. NM_032355.4NP_115731.3  vacuolar fusion protein MON1 homolog A isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC105935
    Consensus CDS
    CCDS2808.2
    Related
    ENSP00000296473.3, ENST00000296473.7
    Conserved Domains (1) summary
    pfam03164
    Location:154554
    Mon1; Trafficking protein Mon1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49908869..49929811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006713345.4XP_006713408.1  vacuolar fusion protein MON1 homolog A isoform X1

    See identical proteins and their annotated locations for XP_006713408.1

    UniProtKB/Swiss-Prot
    Q86VX9
    Related
    ENSP00000494452.1, ENST00000645862.1
    Conserved Domains (1) summary
    pfam03164
    Location:154554
    Mon1; Trafficking protein Mon1
  2. XM_011534160.1XP_011532462.1  vacuolar fusion protein MON1 homolog A isoform X1

    See identical proteins and their annotated locations for XP_011532462.1

    UniProtKB/Swiss-Prot
    Q86VX9
    Conserved Domains (1) summary
    pfam03164
    Location:154554
    Mon1; Trafficking protein Mon1
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