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ETR1 Signal transduction histidine kinase, hybrid-type, ethylene sensor [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842951, updated on 7-Sep-2023

Summary

Gene symbol
ETR1
Gene description
Signal transduction histidine kinase, hybrid-type, ethylene sensor
Primary source
Araport:AT1G66340
Locus tag
AT1G66340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtETR1; EIN1; ETHYLENE INSENSITIVE 1; ETHYLENE RESPONSE; ETHYLENE RESPONSE 1; ETR; HISTIDINE KINASE ETR1; T27F4.9; T27F4_9
Summary
Similar to prokaryote sensory transduction proteins. Contains a histidine kinase and a response regulator domain. Homodimer. Membrane component. Binds ethylene. Mutations affect ethylene binding and metabolism of other plant hormones such as auxin, cytokinins, ABA and gibberellic acid. Ethylene receptor. Has histidine kinase activity. Is regulated by RTE1. Mutations in ETR1 block ethylene stimulation of flavonol synthesis.
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Genomic context

See ETR1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Sequence:
Chromosome: 1; NC_003070.9 (24734162..24737756)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box/RNI-like superfamily protein Neighboring gene senescence-associated family protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene ncRNA Neighboring gene RGA-like 1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_105305.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ethylene binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ethylene receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables phosphorelay sensor kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein histidine kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein histidine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein histidine kinase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cytokinin metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within defense response TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within defense response by callose deposition in cell wall IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within detection of ethylene stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within hydrogen peroxide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within negative regulation of ethylene-activated signaling pathway TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within phloem or xylem histogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of seedling development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to auxin IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to ethylene IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to gibberellin IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to insect IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to molecule of bacterial origin IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to salt stress IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within seed dormancy process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within sugar mediated signaling pathway TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Signal transduction histidine kinase, hybrid-type, ethylene sensor
NP_176808.3
  • ETHYLENE RESPONSE 1 (ETR1); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, homodimeric (InterPro:IPR009082), Signal transduction histidine kinase, core (InterPro:IPR005467), Signal transduction histidine kinase, hybrid-type, ethylene sensor (InterPro:IPR014525), ATPase-like, ATP-binding domain (InterPro:IPR003594), CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789), Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661), GAF (InterPro:IPR003018), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); BEST Arabidopsis thaliana protein match is: ethylene response sensor 1 (TAIR:AT2G40940.1); Has 102721 Blast hits to 98263 proteins in 3046 species: Archae - 757; Bacteria - 90102; Metazoa - 18; Fungi - 1611; Plants - 2314; Viruses - 21; Other Eukaryotes - 7898 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    24734162..24737756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105305.4NP_176808.3  Signal transduction histidine kinase, hybrid-type, ethylene sensor [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176808.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49333
    UniProtKB/TrEMBL
    A0A5S9WSS5
    Conserved Domains (4) summary
    smart00387
    Location:455581
    HATPase_c; Histidine kinase-like ATPases
    smart00388
    Location:343408
    HisKA; His Kinase A (phosphoacceptor) domain
    cd00156
    Location:613729
    REC; Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; ...
    pfam01590
    Location:158307
    GAF; GAF domain