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AMT1;2 ammonium transporter 1;2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842786, updated on 18-Sep-2024

Summary

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Official Symbol
AMT1;2
Official Full Name
ammonium transporter 1;2
Primary source
TAIR:AT1G64780
Locus tag
AT1G64780
See related
Araport:AT1G64780
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ammonium transporter 1;2; ATAMT1;2
Summary
encodes an ammonium transporter protein believed to act as a high affinity transporter. It is expressed in the root, primarily in endodermal and cortical cells, and contributes to ammonium uptake in the root.
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Genomic context

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Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_003070.9 (24060640..24062804, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene NDH-dependent cyclic electron flow 1 Neighboring gene ILITYHIA Neighboring gene uncharacterized protein Neighboring gene DNA binding / transcription factor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A twin histidine motif is the core structure for high-affinity substrate selection in plant ammonium transporters. Ganz P, et al. J Biol Chem, 2020 Mar 6. PMID 31988244, Free PMC Article
  2. A pore-occluding phenylalanine gate prevents ion slippage through plant ammonium transporters. Ganz P, et al. Sci Rep, 2019 Nov 14. PMID 31727964, Free PMC Article
  3. The organization of high-affinity ammonium uptake in Arabidopsis roots depends on the spatial arrangement and biochemical properties of AMT1-type transporters. Yuan L, et al. Plant Cell, 2007 Aug. PMID 17693533, Free PMC Article
  4. HY5 regulates nitrite reductase 1 (NIR1) and ammonium transporter1;2 (AMT1;2) in Arabidopsis seedlings. Huang L, et al. Plant Sci, 2015 Sep. PMID 26259199, Free PMC Article
  5. Nematode-induced changes of transporter gene expression in Arabidopsis roots. Hammes UZ, et al. Mol Plant Microbe Interact, 2005 Dec. PMID 16478044

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A pore-occluding phenylalanine gate prevents ion slippage through plant ammonium transporters.
    Title: A pore-occluding phenylalanine gate prevents ion slippage through plant ammonium transporters.
  2. A twin histidine motif is the core structure for high-affinity substrate selection in plant ammonium transporters.
    Title: A twin histidine motif is the core structure for high-affinity substrate selection in plant ammonium transporters.
  3. HY5 positively regulates nitrite reductase gene NIR1 and negatively regulates the ammonium transporter gene AMT1;2 under all nitrogen and light conditions tested.
    Title: HY5 regulates nitrite reductase 1 (NIR1) and ammonium transporter1;2 (AMT1;2) in Arabidopsis seedlings.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_105152.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ammonium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables ammonium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within methylammonium transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to nematode HEP PubMed 
Component Evidence Code Pubs
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ammonium transporter 1;2
NP_176658.1
  • ammonium transporter 1;2 (AMT1;2); CONTAINS InterPro DOMAIN/s: Ammonium transporter (InterPro:IPR001905), Ammonium transporter, conserved site (InterPro:IPR018047); BEST Arabidopsis thaliana protein match is: ammonium transporter 1;1 (TAIR:AT4G13510.1); Has 11676 Blast hits to 11662 proteins in 2073 species: Archae - 224; Bacteria - 4692; Metazoa - 520; Fungi - 427; Plants - 507; Viruses - 0; Other Eukaryotes - 5306 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    24060640..24062804 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105152.3 → NP_176658.1  ammonium transporter 1;2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176658.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SQH8, Q9ZPJ8
    UniProtKB/TrEMBL
    A0A178WB01, A0A5S9WPC1
    Conserved Domains (1) summary
    TIGR00836
    Location:53 → 479
    amt; ammonium transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZPJ8.1

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