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SLC37A3 solute carrier family 37 member 3 [ Homo sapiens (human) ]

Gene ID: 84255, updated on 23-Nov-2021

Summary

Official Symbol
SLC37A3provided by HGNC
Official Full Name
solute carrier family 37 member 3provided by HGNC
Primary source
HGNC:HGNC:20651
See related
Ensembl:ENSG00000157800 MIM:619137
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SPX3
Expression
Ubiquitous expression in endometrium (RPKM 19.0), thyroid (RPKM 9.8) and 25 other tissues See more
Orthologs
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Genomic context

See SLC37A3 in Genome Data Viewer
Location:
7q34
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (140333752..140398530, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (140033552..140098330, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375534 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 6 Neighboring gene RNA, 5S ribosomal pseudogene 247 Neighboring gene RNA, 5S ribosomal pseudogene 248 Neighboring gene RAB19, member RAS oncogene family Neighboring gene nucleoside diphosphate kinase, mitochondrial-like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16367, MGC32939

General protein information

Preferred Names
sugar phosphate exchanger 3
Names
solute carrier family 37 (glycerol-3-phosphate transporter), member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287498.2NP_001274427.1  sugar phosphate exchanger 3 isoform 3

    See identical proteins and their annotated locations for NP_001274427.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon in the 3' coding region, compared to variant 1. It encodes isoform 3, which is shorter than isoform 1.
    Source sequence(s)
    AK074823, BC046567, BM669953, DB481623
    Consensus CDS
    CCDS75669.1
    UniProtKB/Swiss-Prot
    Q8NCC5
    Related
    ENSP00000397481.2, ENST00000447932.6
    Conserved Domains (1) summary
    cl27298
    Location:14463
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  2. NM_001363373.1NP_001350302.1  sugar phosphate exchanger 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC093087
    Conserved Domains (1) summary
    cl27298
    Location:14410
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  3. NM_001363374.1NP_001350303.1  sugar phosphate exchanger 3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AK074823, BC046567, BM669953, DA750092, DB481623
    Conserved Domains (1) summary
    cl27298
    Location:14358
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  4. NM_001363375.1NP_001350304.1  sugar phosphate exchanger 3 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AK074823, BC046567, BM669953, CX752660, DA064851, DB481623
    Conserved Domains (1) summary
    cl27298
    Location:14398
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  5. NM_001363376.1NP_001350305.1  sugar phosphate exchanger 3 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC093087
    Conserved Domains (1) summary
    cl27298
    Location:14391
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  6. NM_001363377.1NP_001350306.1  sugar phosphate exchanger 3 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC093087
    Conserved Domains (1) summary
    cl27298
    Location:14189
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  7. NM_001363378.1NP_001350307.1  sugar phosphate exchanger 3 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AK074823, BC046567, BM669953, DA582415, DB481623
    Conserved Domains (1) summary
    cl27298
    Location:14253
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
  8. NM_032295.4NP_115671.1  sugar phosphate exchanger 3 isoform 2

    See identical proteins and their annotated locations for NP_115671.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks three exons in the 3' coding region, resulting in a frameshift, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK074823, AL136583, BC028380, BM669953, DB481623
    Consensus CDS
    CCDS5858.1
    UniProtKB/Swiss-Prot
    Q8NCC5
    Related
    ENSP00000343358.3, ENST00000340308.7
    Conserved Domains (1) summary
    cd06174
    Location:84341
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  9. NM_207113.3NP_996996.1  sugar phosphate exchanger 3 isoform 1

    See identical proteins and their annotated locations for NP_996996.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK074823, AL136583, BC028380, BM669953, DB481623
    Consensus CDS
    CCDS5859.1
    UniProtKB/Swiss-Prot
    Q8NCC5
    Related
    ENSP00000321498.9, ENST00000326232.14
    Conserved Domains (1) summary
    cl27298
    Location:14479
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]

RNA

  1. NR_156489.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC093087
  2. NR_156490.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC093087
  3. NR_156491.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC093087
  4. NR_156492.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC093087, AK074823, AK299276, AL691676, BC046567, BM669953, CN261821, DC376346

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    140333752..140398530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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