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AXR3 AUX/IAA transcriptional regulator family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839568, updated on 18-Sep-2024
Official Symbol
AXR3
Official Full Name
AUX/IAA transcriptional regulator family protein
Primary source
TAIR:AT1G04250
Locus tag
AT1G04250
See related
Araport:AT1G04250
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtIAA17; AUXIN RESISTANT 3; F19P19.31; F19P19_31; IAA17; indole-3-acetic acid inducible 17
Summary
Transcription regulator acting as repressor of auxin-inducible gene expression. Auxin-inducible AUX/IAA gene. Short-lived nuclear protein with four conserved domains. Domain III has homology to beta alpha alpha dimerization and DNA binding domains. Involved in auxin signaling. Auxin induces the degradation of the protein in a dosage-dependent manner in a process mediated by AtRac1. Auxin induced the relocalization of the protein within the nucleus from a diffused nucleoplasmic pattern to a discrete particulated pattern named nuclear protein bodies or NPB in a process also mediated by Rac1. Colocalizes with SCF, CSN and 26S proteasome components.
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Location:
chromosome: 1
Exon count:
5
Sequence:
Chromosome: 1; NC_003070.9 (1136078..1138663)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene rRNA-processing EFG1-like protein (DUF2361) Neighboring gene AUX/IAA transcriptional regulator family protein Neighboring gene ncRNA Neighboring gene CAMV movement protein interacting protein 7 Neighboring gene cytosolic ribosomal protein S15 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein

Genomic Sequence:
NC_003070.9

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description
NM_100306.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
 
Preferred Names
AUX/IAA transcriptional regulator family protein
NP_171921.1
  • AUXIN RESISTANT 3 (AXR3); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), AUX/IAA protein (InterPro:IPR003311); BEST Arabidopsis thaliana protein match is: indole-3-acetic acid inducible 14 (TAIR:AT4G14550.1); Has 1763 Blast hits to 1762 proteins in 78 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1762; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1136078..1138663
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100306.4NP_171921.1  AUX/IAA transcriptional regulator family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171921.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49162, P93830
    UniProtKB/TrEMBL
    A0A178WIK9, A0A5S9SIX8
    Conserved Domains (1) summary
    pfam02309
    Location:11220
    AUX_IAA; AUX/IAA family