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CUL2 cullin 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839415, updated on 18-Sep-2024

Summary

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Official Symbol
CUL2
Official Full Name
cullin 2
Primary source
TAIR:AT1G02980
Locus tag
AT1G02980
See related
Araport:AT1G02980
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCUL2; cullin 2; F22D16.2; F22D16_2
Summary
encodes an Arabidopsis cullin
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Sequence:
Chromosome: 1; NC_003070.9 (677360..681378)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene WEE1-like kinase Neighboring gene uncharacterized protein Neighboring gene peroxin 6 Neighboring gene Phototropic-responsive NPH3 family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Risseeuw EP, et al. Plant J, 2003 Jun. PMID 12795696
  2. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001331372.1
NM_100179.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in chloroplast envelope HDA PubMed 

General protein information

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Preferred Names
cullin 2
NP_001318910.1
  • cullin 2 (CUL2); FUNCTIONS IN: ubiquitin protein ligase binding; INVOLVED IN: cell cycle, ubiquitin-dependent protein catabolic process; LOCATED IN: SCF ubiquitin ligase complex, chloroplast envelope; EXPRESSED IN: sperm cell, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin protein, neddylation domain (InterPro:IPR019559), Cullin, N-terminal (InterPro:IPR001373), Cullin repeat-like-containing domain (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: Cullin family protein (TAIR:AT1G43140.1); Has 2240 Blast hits to 2201 proteins in 240 species: Archae - 0; Bacteria - 18; Metazoa - 947; Fungi - 508; Plants - 372; Viruses - 0; Other Eukaryotes - 395 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    677360..681378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001331372.1 → NP_001318910.1  cullin 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GY26, Q9SRZ0
    UniProtKB/TrEMBL
    A0A178W3E2, A0A5S9SAT6, A0A654E6M7
    Conserved Domains (2) summary
    smart00884
    Location:669 → 736
    Cullin_Nedd8; Cullin protein neddylation domain
    pfam00888
    Location:12 → 645
    Cullin; Cullin family

  2. NM_100179.4 → NP_171797.2  cullin 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171797.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GY26, Q9SRZ0
    UniProtKB/TrEMBL
    A0A178W3E2, A0A5S9SAT6, A0A654E6M7
    Conserved Domains (2) summary
    smart00884
    Location:669 → 736
    Cullin_Nedd8; Cullin protein neddylation domain
    pfam00888
    Location:12 → 645
    Cullin; Cullin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SRZ0.1

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