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TMT1 tonoplast monosaccharide transporter1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838676, updated on 18-Sep-2024

Summary

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Official Symbol
TMT1
Official Full Name
tonoplast monosaccharide transporter1
Primary source
TAIR:AT1G20840
Locus tag
AT1G20840
See related
Araport:AT1G20840
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtTMT1; F9H16.18; F9H16_18; tonoplast monosaccharide transporter1
Summary
The protein encoded by this gene is found in the tonoplast (vacuole membrane) of Arabidopsis cells. The gene is expressed at highest levels in juvenile (sink) and adult (source) leaves, followed by flower tissues.
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Genomic context

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Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (7244939..7248494, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene tRNA-Trp Neighboring gene multiple chloroplast division site 1 Neighboring gene ncRNA Neighboring gene xylem cysteine peptidase 2 Neighboring gene phosphate transporter 1;8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased activity of the vacuolar monosaccharide transporter TMT1 alters cellular sugar partitioning, sugar signaling, and seed yield in Arabidopsis. Wingenter K, et al. Plant Physiol, 2010 Oct. PMID 20709831, Free PMC Article
  2. A member of the mitogen-activated protein 3-kinase family is involved in the regulation of plant vacuolar glucose uptake. Wingenter K, et al. Plant J, 2011 Dec. PMID 21838775
  3. Proton-driven sucrose symport and antiport are provided by the vacuolar transporters SUC4 and TMT1/2. Schulz A, et al. Plant J, 2011 Oct. PMID 21668536
  4. Molecular identification and physiological characterization of a novel monosaccharide transporter from Arabidopsis involved in vacuolar sugar transport. Wormit A, et al. Plant Cell, 2006 Dec. PMID 17158605, Free PMC Article
  5. Arabidopsis J-protein J20 delivers the first enzyme of the plastidial isoprenoid pathway to protein quality control. Pulido P, et al. Plant Cell, 2013 Oct. PMID 24104567, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AtSUC4 most likely catalyses proton-coupled sucrose export from the vacuole within the Arabidopsis cell. However, TMT1/2 probably represents a proton-coupled antiporter capable of high-capacity loading of glucose and sucrose into the vacuole.
    Title: Proton-driven sucrose symport and antiport are provided by the vacuolar transporters SUC4 and TMT1/2.
  2. VIK-dependent phosphorylation stimulates TMT1 transport activity.
    Title: A member of the mitogen-activated protein 3-kinase family is involved in the regulation of plant vacuolar glucose uptake.
  3. Increased TMT1 activity induced modified subcellular sugar compartmentation, altered cellular sugar sensing, affected assimilate allocation, increased the seed biomass, and accelerated early plant development.
    Title: Increased activity of the vacuolar monosaccharide transporter TMT1 alters cellular sugar partitioning, sugar signaling, and seed yield in Arabidopsis.
  4. These results indicate that TMT1 is involved in vacuolar monosaccharide transport and plays a major role during stress responses.[TMT1]
    Title: Molecular identification and physiological characterization of a novel monosaccharide transporter from Arabidopsis involved in vacuolar sugar transport.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001332471.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables nucleoside transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to fructose IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to glucose IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to nematode HEP PubMed 
involved_in response to salt IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to sucrose IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plant-type vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
tonoplast monosaccharide transporter1
NP_001319055.1
  • tonoplast monosaccharide transporter1 (TMT1); FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity, nucleoside transmembrane transporter activity; INVOLVED IN: in 6 processes; LOCATED IN: plant-type vacuole membrane, plasma membrane, vacuole, membrane; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: tonoplast monosaccharide transporter2 (TAIR:AT4G35300.4); Has 47782 Blast hits to 35006 proteins in 2411 species: Archae - 763; Bacteria - 22324; Metazoa - 7189; Fungi - 11789; Plants - 3723; Viruses - 0; Other Eukaryotes - 1994 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    7244939..7248494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101937.6 → NP_173508.1  tonoplast monosaccharide transporter1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173508.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q96290, Q9LM67, Q9SYQ3
    UniProtKB/TrEMBL
    A0A178W059, A0A5S9VBJ9
    Conserved Domains (1) summary
    cl28910
    Location:10 → 208
    MFS; Major Facilitator Superfamily

  2. NM_001332471.1 → NP_001319055.1  tonoplast monosaccharide transporter1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q96290, Q9LM67, Q9SYQ3
    UniProtKB/TrEMBL
    A0A178W059, A0A5S9VBJ9
    Conserved Domains (1) summary
    cl28910
    Location:10 → 208
    MFS; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96290.2

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