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ZIP2 ZRT/IRT-like protein 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836071, updated on 18-Sep-2024

Summary

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Official Symbol
ZIP2
Official Full Name
ZRT/IRT-like protein 2
Primary source
TAIR:AT5G59520
Locus tag
AT5G59520
See related
Araport:AT5G59520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtZIP2; F2O15.25; F2O15_25; ZRT/IRT-like protein 2
Summary
encodes a metal ion transporter whose expression is regulated by copper.
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Genomic context

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Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (23991213..23992908, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ROTUNDIFOLIA like 5 Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene zinc finger (C3HC4-type RING finger) family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis. Wintz H, et al. J Biol Chem, 2003 Nov 28. PMID 13129917
  2. Phylogenetic relationships within cation transporter families of Arabidopsis. Mäser P, et al. Plant Physiol, 2001 Aug. PMID 11500563, Free PMC Article
  3. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_125344.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper ion transmembrane transporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables metal ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion transmembrane transporter activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within zinc ion transport TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
ZRT/IRT-like protein 2
NP_200760.1
  • ZRT/IRT-like protein 2 (ZIP2); FUNCTIONS IN: copper ion transmembrane transporter activity, zinc ion transmembrane transporter activity, transferase activity, transferring glycosyl groups; INVOLVED IN: zinc ion transport, response to copper ion; LOCATED IN: plasma membrane; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Zinc/iron permease (InterPro:IPR003689); BEST Arabidopsis thaliana protein match is: zinc transporter 11 precursor (TAIR:AT1G55910.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    23991213..23992908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125344.3 → NP_200760.1  ZRT/IRT-like protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200760.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81124, Q9LTH9
    UniProtKB/TrEMBL
    A0A5S9YFJ0, A0A654GD36, Q0WSL6
    Conserved Domains (1) summary
    pfam02535
    Location:61 → 350
    Zip; ZIP Zinc transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LTH9.1

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