Format

Send to:

Choose Destination

PICALM phosphatidylinositol binding clathrin assembly protein [ Homo sapiens (human) ]

Gene ID: 8301, updated on 3-Jun-2018
Official Symbol
PICALMprovided by HGNC
Official Full Name
phosphatidylinositol binding clathrin assembly proteinprovided by HGNC
Primary source
HGNC:HGNC:15514
See related
Ensembl:ENSG00000073921 MIM:603025; Vega:OTTHUMG00000166981
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LAP; CALM; CLTH
Summary
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Expression
Ubiquitous expression in fat (RPKM 64.4), appendix (RPKM 52.9) and 25 other tissues See more
Orthologs
See PICALM in Genome Data Viewer
Location:
11q14.2
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (85957171..86069881, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (85668214..85780923, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 83 Neighboring gene adenosylhomocysteinase pseudogene 6 Neighboring gene solute carrier family 25 member 1 pseudogene 1 Neighboring gene RNA, U6 small nuclear 560, pseudogene Neighboring gene uncharacterized LOC107984426

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
NHGRI GWA Catalog
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
NHGRI GWA Catalog
Genome-wide association study of Alzheimer's disease.
NHGRI GWA Catalog
Genome-wide association study of Tourette's syndrome.
NHGRI GWA Catalog
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
NHGRI GWA Catalog
The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
NHGRI GWA Catalog
  • Cargo recognition for clathrin-mediated endocytosis, organism-specific biosystem (from REACTOME)
    Cargo recognition for clathrin-mediated endocytosis, organism-specific biosystemRecruitment of plasma membrane-localized cargo into clathrin-coated endocytic vesicles is mediated by interaction with a variety of clathrin-interacting proteins collectively called CLASPs (clathrin-...
  • Clathrin derived vesicle budding, organism-specific biosystem (from REACTOME)
    Clathrin derived vesicle budding, organism-specific biosystemThere at least two classes of clathrin coated vesicles in cells, one predominantly Golgi-associated, involved in budding from the trans-Golgi network and the other at the plasma membrane. Here the cl...
  • Clathrin-mediated endocytosis, organism-specific biosystem (from REACTOME)
    Clathrin-mediated endocytosis, organism-specific biosystemClathrin-mediated endocytosis (CME) is one of a number of process that control the uptake of material from the plasma membrane, and leads to the formation of clathrin-coated vesicles (Pearse et al, 1...
  • Golgi Associated Vesicle Biogenesis, organism-specific biosystem (from REACTOME)
    Golgi Associated Vesicle Biogenesis, organism-specific biosystemProteins that have been synthesized, processed and sorted eventually reach the final steps of the secretory pathway. This pathway is responsible not only for proteins that are secreted from the cell ...
  • Membrane Trafficking, organism-specific biosystem (from REACTOME)
    Membrane Trafficking, organism-specific biosystemThe secretory membrane system allows a cell to regulate delivery of newly synthesized proteins, carbohydrates, and lipids to the cell surface, a necessity for growth and homeostasis. The system is ma...
  • Vesicle-mediated transport, organism-specific biosystem (from REACTOME)
    Vesicle-mediated transport, organism-specific biosystemThe transit of proteins and other cargo through the cell requires a cellular transport process in which transported substances are moved in membrane-bounded vesicles. Transported substances are enclo...
  • trans-Golgi Network Vesicle Budding, organism-specific biosystem (from REACTOME)
    trans-Golgi Network Vesicle Budding, organism-specific biosystemAfter passing through the Golgi complex, secretory cargo is packaged into post-Golgi transport intermediates (post-Golgi), which translocate plus-end directed along microtubules to the plasma membran...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
1-phosphatidylinositol binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Rab GTPase binding IPI
Inferred from Physical Interaction
more info
PubMed 
cadherin binding HDA PubMed 
clathrin adaptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
clathrin binding IDA
Inferred from Direct Assay
more info
PubMed 
clathrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
clathrin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
clathrin heavy chain binding IDA
Inferred from Direct Assay
more info
PubMed 
low-density lipoprotein particle receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
phosphatidylinositol-4,5-bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
axonogenesis IEA
Inferred from Electronic Annotation
more info
 
cargo loading into vesicle IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
clathrin coat assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
clathrin-dependent endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 
endosomal transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
hemopoiesis IEA
Inferred from Electronic Annotation
more info
 
iron ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
iron ion import across plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
learning or memory ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
membrane bending IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane organization TAS
Traceable Author Statement
more info
 
modulation of age-related behavioral decline ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of protein localization to cell surface IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of receptor-mediated endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of GTPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of amyloid-beta clearance ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of amyloid-beta formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of amyloid-beta formation TAS
Traceable Author Statement
more info
PubMed 
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of clathrin-dependent endocytosis NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of neuron death IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex assembly TAS
Traceable Author Statement
more info
PubMed 
receptor internalization IMP
Inferred from Mutant Phenotype
more info
PubMed 
receptor-mediated endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
receptor-mediated endocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 
NOT regulation of amyloid-beta formation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein localization IDA
Inferred from Direct Assay
more info
PubMed 
regulation of vesicle size IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic vesicle maturation ISS
Inferred from Sequence or Structural Similarity
more info
 
transcytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
vesicle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
vesicle-mediated transport TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with AP-2 adaptor complex IDA
Inferred from Direct Assay
more info
PubMed 
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with clathrin coat of coated pit IDA
Inferred from Direct Assay
more info
PubMed 
clathrin-coated endocytic vesicle NAS
Non-traceable Author Statement
more info
PubMed 
clathrin-coated pit IDA
Inferred from Direct Assay
more info
PubMed 
clathrin-coated pit IMP
Inferred from Mutant Phenotype
more info
PubMed 
clathrin-coated pit ISS
Inferred from Sequence or Structural Similarity
more info
 
clathrin-coated vesicle IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
early endosome IDA
Inferred from Direct Assay
more info
PubMed 
endosome to plasma membrane transport vesicle IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
intrinsic component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
membrane HDA PubMed 
neurofibrillary tangle IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
postsynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
presynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
phosphatidylinositol-binding clathrin assembly protein
Names
clathrin assembly lymphoid myeloid leukemia protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_028942.1 RefSeqGene

    Range
    5001..117710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001008660.2NP_001008660.1  phosphatidylinositol-binding clathrin assembly protein isoform 2

    See identical proteins and their annotated locations for NP_001008660.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon, but has an additional downstream in-frame exon, in the coding region, as compared to variant 1. The encoded isoform 2 thus lacks an internal segment and also has an additional segment, as compared to isoform 1.
    Source sequence(s)
    AB210017, AK128786, BC048259, BC073961, CA415536
    Consensus CDS
    CCDS31653.1
    UniProtKB/Swiss-Prot
    Q13492
    UniProtKB/TrEMBL
    A0A024R5L7
    Related
    ENSP00000436958.1, OTTHUMP00000234630, ENST00000532317.5, OTTHUMT00000392220
    Conserved Domains (2) summary
    COG4223
    Location:268366
    COG4223; Uncharacterized conserved protein [Function unknown]
    pfam07651
    Location:24282
    ANTH; ANTH domain
  2. NM_001206946.1NP_001193875.1  phosphatidylinositol-binding clathrin assembly protein isoform 3

    See identical proteins and their annotated locations for NP_001193875.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) has an alternate splice site in the coding sequence, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AB210017, AK128786, BC048259, CA415536
    Consensus CDS
    CCDS55784.1
    UniProtKB/Swiss-Prot
    Q13492
    Related
    ENSP00000433846.1, OTTHUMP00000234631, ENST00000526033.5, OTTHUMT00000392221
    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  3. NM_001206947.1NP_001193876.1  phosphatidylinositol-binding clathrin assembly protein isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has an alternate 5' exon, resulting in a downstream AUG start codon, and lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus and lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AK128786, AK300275, BC073961, CA415536, DC300074
    Consensus CDS
    CCDS55783.1
    UniProtKB/Swiss-Prot
    Q13492
    Related
    ENSP00000434884.1, OTTHUMP00000234635, ENST00000528398.5, OTTHUMT00000392226
    Conserved Domains (2) summary
    pfam07651
    Location:1231
    ANTH; ANTH domain
    pfam08287
    Location:214293
    DASH_Spc19; Spc19
  4. NM_007166.3NP_009097.2  phosphatidylinositol-binding clathrin assembly protein isoform 1

    See identical proteins and their annotated locations for NP_009097.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AB210017, AK128786, BC048259, CA415536
    Consensus CDS
    CCDS8272.1
    UniProtKB/Swiss-Prot
    Q13492
    UniProtKB/TrEMBL
    A0A024R5P1
    Related
    ENSP00000377015.3, OTTHUMP00000234633, ENST00000393346.7, OTTHUMT00000392224
    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

    Range
    85957171..86069881 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017018388.2XP_016873877.1  phosphatidylinositol-binding clathrin assembly protein isoform X29

  2. XM_011545293.2XP_011543595.1  phosphatidylinositol-binding clathrin assembly protein isoform X23

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:492571
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  3. XM_017018387.2XP_016873876.1  phosphatidylinositol-binding clathrin assembly protein isoform X28

  4. XM_017018384.2XP_016873873.1  phosphatidylinositol-binding clathrin assembly protein isoform X24

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  5. XM_005274335.3XP_005274392.1  phosphatidylinositol-binding clathrin assembly protein isoform X19

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  6. XM_005274336.3XP_005274393.1  phosphatidylinositol-binding clathrin assembly protein isoform X21

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  7. XM_005274332.3XP_005274389.1  phosphatidylinositol-binding clathrin assembly protein isoform X16

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:523602
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  8. XM_005274340.3XP_005274397.1  phosphatidylinositol-binding clathrin assembly protein isoform X30

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  9. XM_017018386.2XP_016873875.1  phosphatidylinositol-binding clathrin assembly protein isoform X27

  10. XM_017018383.2XP_016873872.1  phosphatidylinositol-binding clathrin assembly protein isoform X22

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  11. XM_005274333.3XP_005274390.1  phosphatidylinositol-binding clathrin assembly protein isoform X17

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  12. XM_017018381.2XP_016873870.1  phosphatidylinositol-binding clathrin assembly protein isoform X12

  13. XM_006718700.3XP_006718763.1  phosphatidylinositol-binding clathrin assembly protein isoform X5

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:566645
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  14. XM_024448700.1XP_024304468.1  phosphatidylinositol-binding clathrin assembly protein isoform X11

    Conserved Domains (2) summary
    COG4223
    Location:268366
    COG4223; Uncharacterized conserved protein [Function unknown]
    pfam07651
    Location:24282
    ANTH; ANTH domain
  15. XM_006718699.3XP_006718762.1  phosphatidylinositol-binding clathrin assembly protein isoform X3

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:571650
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  16. XM_005274334.3XP_005274391.1  phosphatidylinositol-binding clathrin assembly protein isoform X18

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  17. XM_005274329.4XP_005274386.1  phosphatidylinositol-binding clathrin assembly protein isoform X13

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  18. XM_005274325.3XP_005274382.1  phosphatidylinositol-binding clathrin assembly protein isoform X6

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  19. XM_005274328.3XP_005274385.1  phosphatidylinositol-binding clathrin assembly protein isoform X10

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  20. XM_005274337.3XP_005274394.1  phosphatidylinositol-binding clathrin assembly protein isoform X25

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  21. XM_005274331.3XP_005274388.1  phosphatidylinositol-binding clathrin assembly protein isoform X15

    See identical proteins and their annotated locations for XP_005274388.1

    UniProtKB/Swiss-Prot
    Q13492
    Related
    ENSP00000348718.5, OTTHUMP00000234637, ENST00000356360.9
    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  22. XM_005274327.3XP_005274384.1  phosphatidylinositol-binding clathrin assembly protein isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  23. XM_005274324.3XP_005274381.1  phosphatidylinositol-binding clathrin assembly protein isoform X4

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  24. XM_005274326.3XP_005274383.1  phosphatidylinositol-binding clathrin assembly protein isoform X8

    See identical proteins and their annotated locations for XP_005274383.1

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  25. XM_005274322.3XP_005274379.1  phosphatidylinositol-binding clathrin assembly protein isoform X1

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:578657
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  26. XM_017018382.2XP_016873871.1  phosphatidylinositol-binding clathrin assembly protein isoform X20

  27. XM_006718701.4XP_006718764.1  phosphatidylinositol-binding clathrin assembly protein isoform X7

    Conserved Domains (2) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
  28. XM_005274323.3XP_005274380.1  phosphatidylinositol-binding clathrin assembly protein isoform X2

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:573652
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  29. XM_005274330.3XP_005274387.1  phosphatidylinositol-binding clathrin assembly protein isoform X14

    Conserved Domains (3) summary
    pfam07651
    Location:19282
    ANTH; ANTH domain
    pfam08287
    Location:265344
    DASH_Spc19; Spc19
    pfam11029
    Location:528607
    DAZAP2; DAZ associated protein 2 (DAZAP2)
  30. XM_017018385.2XP_016873874.1  phosphatidylinositol-binding clathrin assembly protein isoform X26

Support Center