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DRL1 dihydroflavonol 4-reductase-like1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829695, updated on 7-Sep-2023

Summary

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Gene symbol
DRL1
Gene description
dihydroflavonol 4-reductase-like1
Primary source
Araport:AT4G35420
Locus tag
AT4G35420
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
dihydroflavonol 4-reductase-like1; F15J1.1; tetraketide alpha-pyrone reductase 1; TKPR1
Summary
Encodes DRL1 (Dihydroflavonol 4-reductase-like1), a closely related homolog of the rice anther-specific gene OsDFR2. DRL1 may be involved in a metabolic pathway essential for pollen wall development and male fertility. Mutant plants have impaired pollen formation and seed production.
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Genomic context

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Location:
chromosome: 4
Exon count:
6
Sequence:
Chromosome: 4; NC_003075.7 (16833933..16835619, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene AT-hook protein of GA feedback 1 Neighboring gene pseudo Neighboring gene Clathrin adaptor complex small chain family protein Neighboring gene uncharacterized protein Neighboring gene chloride channel E Neighboring gene ankyrin repeat-containing protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An anther-specific dihydroflavonol 4-reductase-like gene (DRL1) is essential for male fertility in Arabidopsis. Tang LK, et al. New Phytol, 2009. PMID 19054337
  2. Analysis of TETRAKETIDE α-PYRONE REDUCTASE function in Arabidopsis thaliana reveals a previously unknown, but conserved, biochemical pathway in sporopollenin monomer biosynthesis. Grienenberger E, et al. Plant Cell, 2010 Dec. PMID 21193572, Free PMC Article
  3. Sporopollenin biosynthetic enzymes interact and constitute a metabolon localized to the endoplasmic reticulum of tapetum cells. Lallemand B, et al. Plant Physiol, 2013 Jun. PMID 23632852, Free PMC Article
  4. A large-scale genetic screen in Arabidopsis to identify genes involved in pollen exine production. Dobritsa AA, et al. Plant Physiol, 2011 Oct. PMID 21849515, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DRL1 may have a conserved functional role in male fertility in flowering plants. [DRL1]
    Title: An anther-specific dihydroflavonol 4-reductase-like gene (DRL1) is essential for male fertility in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_119708.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within pollen development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pollen exine formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within seed development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sporopollenin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
dihydroflavonol 4-reductase-like1
NP_195268.2
  • dihydroflavonol 4-reductase-like1 (DRL1); FUNCTIONS IN: coenzyme binding, binding, catalytic activity; INVOLVED IN: seed development, pollen development; LOCATED IN: endomembrane system; EXPRESSED IN: leaf whorl, hypocotyl, sepal, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT1G68540.1); Has 11019 Blast hits to 11006 proteins in 1795 species: Archae - 197; Bacteria - 4697; Metazoa - 293; Fungi - 927; Plants - 2536; Viruses - 49; Other Eukaryotes - 2320 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    16833933..16835619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119708.3 → NP_195268.2  dihydroflavonol 4-reductase-like1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195268.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65487, Q500U8
    UniProtKB/TrEMBL
    A0A178UY38, A0A5S9XYU6, A0A654FW88
    Conserved Domains (1) summary
    cd08958
    Location:8 → 299
    FR_SDR_e; flavonoid reductase (FR), extended (e) SDRs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q500U8.1

Gene LinkOut

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