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FTSZ2-2 Tubulin/FtsZ family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824441, updated on 18-Sep-2024

Summary

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Official Symbol
FTSZ2-2
Official Full Name
Tubulin/FtsZ family protein
Primary source
TAIR:AT3G52750
Locus tag
AT3G52750
See related
Araport:AT3G52750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Summary
Nuclear gene that encodes a plastidial division protein (FtsZ2-2). FtsZ2-2 is involved in chloroplast morphology and internal organisation in addition to participating in chloroplast partition
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (19549604..19553136, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Integral membrane Yip1 family protein Neighboring gene tRNA-Asp

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple FtsZ2 isoforms involved in chloroplast division and biogenesis are developmentally associated with thylakoid membranes in Arabidopsis. Karamoko M, et al. FEBS Lett, 2011 Apr 20. PMID 21439281
  2. Chloroplast targeting of chloroplast division FtsZ2 proteins in Arabidopsis. Fujiwara M, et al. Biochem Biophys Res Commun, 2001 Sep 21. PMID 11554751
  3. GTP-dependent heteropolymer formation and bundling of chloroplast FtsZ1 and FtsZ2. Olson BJ, et al. J Biol Chem, 2010 Jul 2. PMID 20421292, Free PMC Article
  4. Arabidopsis FtsZ2-1 and FtsZ2-2 are functionally redundant, but FtsZ-based plastid division is not essential for chloroplast partitioning or plant growth and development. Schmitz AJ, et al. Mol Plant, 2009 Nov. PMID 19995726
  5. Colocalization of plastid division proteins in the chloroplast stromal compartment establishes a new functional relationship between FtsZ1 and FtsZ2 in higher plants. McAndrew RS, et al. Plant Physiol, 2001 Dec. PMID 11743110, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results suggest that ARC3 directly inhibits Z-ring assembly through interaction with FtsZ2 in heteropolymers and that ARC3 activity is spatially regulated by MinD1 and MinE1 to permit Z-ring assembly at the mid-plastid.
    Title: Chloroplast division protein ARC3 regulates chloroplast FtsZ-ring assembly and positioning in arabidopsis through interaction with FtsZ2.
  2. AtFtsZ2 is phosphorylated in vivo in Arabidopsis and that PGK1 (phosphoglycerate kinase 1) interacts with AtFtsZ2 in planta, suggesting a possible role in FtsZ phosphorylation.
    Title: In vivo phosphorylation of FtsZ2 in Arabidopsis thaliana.
  3. Data show that FtsZ2-1 is essential for chloroplast division and that FtsZ2-2 plays a specific role in chloroplast morphology and internal organisation in addition to participating in chloroplast partition.
    Title: Multiple FtsZ2 isoforms involved in chloroplast division and biogenesis are developmentally associated with thylakoid membranes in Arabidopsis.
  4. Evolution of FtsZ-2 in green plants, perhaps arising from an enhanced capacity for the regulation of Z ring composition and activity in vivo.
    Title: GTP-dependent heteropolymer formation and bundling of chloroplast FtsZ1 and FtsZ2.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001339587.1
NM_001339588.1
NM_115135.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTP binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloroplast fission IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within chloroplast organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast thylakoid HDA PubMed 
colocalizes_with chloroplast thylakoid membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in contractile ring IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in plastid stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in thylakoid membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Tubulin/FtsZ family protein
NP_190843.1
  • FTSZ2-2; FUNCTIONS IN: structural molecule activity, GTP binding, GTPase activity; INVOLVED IN: protein polymerization; LOCATED IN: chloroplast stroma, chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cell division protein FtsZ, N-terminal (InterPro:IPR000158), Cell division protein FtsZ, conserved site (InterPro:IPR020805), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: Tubulin/FtsZ family protein (TAIR:AT2G36250.2); Has 10464 Blast hits to 10464 proteins in 3156 species: Archae - 455; Bacteria - 6195; Metazoa - 8; Fungi - 0; Plants - 153; Viruses - 0; Other Eukaryotes - 3653 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19549604..19553136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001339586.1 → NP_001327517.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93ZQ7, Q9LXJ0
    UniProtKB/TrEMBL
    A0A178V810, A0A654FF86
    Conserved Domains (1) summary
    PRK09330
    Location:101 → 465
    PRK09330; cell division protein FtsZ; Validated

  2. NM_115135.3 → NP_190843.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190843.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93ZQ7, Q9LXJ0
    UniProtKB/TrEMBL
    A0A178V810, A0A654FF86
    Conserved Domains (1) summary
    PRK09330
    Location:101 → 465
    PRK09330; cell division protein FtsZ; Validated

  3. NM_001339587.1 → NP_001327516.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93ZQ7, Q9LXJ0
    UniProtKB/TrEMBL
    A0A178V810, A0A654FF86
    Conserved Domains (1) summary
    PRK09330
    Location:101 → 465
    PRK09330; cell division protein FtsZ; Validated

  4. NM_001339588.1 → NP_001327515.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LSJ8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LXJ0.1

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