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ACT2 actin 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821411, updated on 18-Sep-2024

Summary

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Official Symbol
ACT2
Official Full Name
actin 2
Primary source
TAIR:AT3G18780
Locus tag
AT3G18780
See related
Araport:AT3G18780
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
actin 2; DEFORMED ROOT HAIRS 1; DER1; ENHANCER OF LRX1 2; ENL2; FIZ2; FRIZZY AND KINKED SHOOTS 2; LIGHT STRESS-REGULATED 2; LSR2
Summary
Encodes an actin that is constitutively expressed in vegetative structures but not pollen. ACT2 is involved in tip growth of root hairs.
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Genomic context

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Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (6474710..6477204)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene pre-mRNA-splicing factor ISY1-like protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Single Amino Acid Exchange in ACTIN2 Confers Increased Tolerance to Oxidative Stress in Arabidopsis der1-3 Mutant. Kuběnová L, et al. Int J Mol Sci, 2021 Feb 13. PMID 33668638, Free PMC Article
  2. Single-point ACT2 gene mutation in the Arabidopsis root hair mutant der1-3 affects overall actin organization, root growth and plant development. Vaškebová L, et al. Ann Bot, 2018 Nov 3. PMID 29293922, Free PMC Article
  3. Arabidopsis vegetative actin isoforms, AtACT2 and AtACT7, generate distinct filament arrays in living plant cells. Kijima ST, et al. Sci Rep, 2018 Mar 12. PMID 29531328, Free PMC Article
  4. An alternatively spliced domain of the NDC1 NAD(P)H dehydrogenase gene strongly influences the expression of the ACTIN2 reference gene in Arabidopsis thaliana. Wallström SV, et al. Plant Sci, 2012 Feb. PMID 22195593
  5. At5PTase13 modulates cotyledon vein development through regulating auxin homeostasis. Lin WH, et al. Plant Physiol, 2005 Dec. PMID 16299182, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Single Amino Acid Exchange in ACTIN2 Confers Increased Tolerance to Oxidative Stress in Arabidopsis der1-3 Mutant.
    Title: Single Amino Acid Exchange in ACTIN2 Confers Increased Tolerance to Oxidative Stress in Arabidopsis der1-3 Mutant.
  2. different actin isoforms (ACT2 and ACT7) are capable of constructing unique filament arrays, depending on the cell type or tissue.
    Title: Arabidopsis vegetative actin isoforms, AtACT2 and AtACT7, generate distinct filament arrays in living plant cells.
  3. The results suggest that the der1-3 mutation in the ACT2 gene does not influence solely root hair formation process, but also has more general effects on the actin cytoskeleton, plant growth and development.
    Title: Single-point ACT2 gene mutation in the Arabidopsis root hair mutant der1-3 affects overall actin organization, root growth and plant development.
  4. The alternatively spliced 5' domain of NDC1 strongly influences the expression of the functionally unrelated ACTIN2, which is a common reference gene in Arabidopsis thaliana for quantitative RT-PCR.
    Title: An alternatively spliced domain of the NDC1 NAD(P)H dehydrogenase gene strongly influences the expression of the ACTIN2 reference gene in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001338358.1
NM_001338359.1
NM_112764.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to cytokinin IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to far red light IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to high light intensity IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to red light IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within root epidermal cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within root hair cell tip growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within root hair elongation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
actin 2
NP_001319585.1
  • actin 2 (ACT2); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: in 7 processes; LOCATED IN: nucleus, membrane, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Actin, conserved site (InterPro:IPR004001), Actin/actin-like (InterPro:IPR004000), Actin/actin-like conserved site (InterPro:IPR020902); BEST Arabidopsis thaliana protein match is: actin 8 (TAIR:AT1G49240.1); Has 14997 Blast hits to 14643 proteins in 3016 species: Archae - 6; Bacteria - 12; Metazoa - 5603; Fungi - 5165; Plants - 1589; Viruses - 2; Other Eukaryotes - 2620 (source: NCBI BLink).
NP_188508.1
  • actin 2 (ACT2); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: in 7 processes; LOCATED IN: nucleus, membrane, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Actin, conserved site (InterPro:IPR004001), Actin/actin-like (InterPro:IPR004000), Actin/actin-like conserved site (InterPro:IPR020902); BEST Arabidopsis thaliana protein match is: actin 8 (TAIR:AT1G49240.1); Has 15142 Blast hits to 14749 proteins in 3039 species: Archae - 6; Bacteria - 12; Metazoa - 5705; Fungi - 5217; Plants - 1599; Viruses - 2; Other Eukaryotes - 2601 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    6474710..6477204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112764.4 → NP_188508.1  actin 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188508.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q42056, Q96292
    UniProtKB/TrEMBL
    A0A178VJY0, A0A384KW03, B9DHA3, Q0WL95
    Conserved Domains (1) summary
    cl17037
    Location:3 → 377
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  2. NM_001338358.1 → NP_001319585.1  actin 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B9DHA3, F4J8V9

  3. NM_001338359.1 → NP_001327851.1  actin 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q42056, Q96292
    UniProtKB/TrEMBL
    A0A178VJY0, A0A384KW03, B9DHA3, Q0WL95
    Conserved Domains (1) summary
    cl17037
    Location:3 → 377
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96292.1

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