UBP25 ubiquitin-specific protease 25 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: UBP25
Official Full Name: ubiquitin-specific protease 25
Primary source: TAIR:AT3G14400
Locus tag: AT3G14400
See related: Araport:AT3G14400
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ubiquitin-specific protease 25; UBIQUITIN-SPECIFIC PROTEASE 25
Summary: Encodes a ubiquitin-specific protease.
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Genomic context

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See UBP25 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 8

Sequence:: Chromosome: 3; NC_003074.8 (4811486..4815515, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_112299.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: ubiquitin-specific protease 25

NP_566486.1

ubiquitin-specific protease 25 (UBP25); FUNCTIONS IN: ubiquitin-specific protease activity, ubiquitin thiolesterase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 23 (TAIR:AT5G57990.1); Has 8659 Blast hits to 7314 proteins in 254 species: Archae - 0; Bacteria - 9; Metazoa - 4447; Fungi - 1449; Plants - 1041; Viruses - 9; Other Eukaryotes - 1704 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

4811486..4815515 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112299.4 → NP_566486.1 ubiquitin-specific protease 25 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566486.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8VZF5, Q9FPS2, Q9LUK9

UniProtKB/TrEMBL

A0A178VGL4, A0A654F8F7

Conserved Domains (2) summary

cd02661
Location:23 → 333

Peptidase_C19E; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

pfam10163
Location:576 → 652

EnY2; Transcription factor e(y)2