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EMB2654 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818771, updated on 18-Sep-2024

Summary

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Official Symbol
EMB2654
Official Full Name
Tetratricopeptide repeat (TPR)-like superfamily protein
Primary source
TAIR:AT2G41720
Locus tag
AT2G41720
See related
Araport:AT2G41720
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EMBRYO DEFECTIVE 2654; T11A7.18; T11A7_18
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Genomic context

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Location:
chromosome: 2
Exon count:
9
Sequence:
Chromosome: 2; NC_003071.7 (17403603..17407325, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene camphor resistance CrcB family protein Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene ncRNA Neighboring gene calcium-binding site protein Neighboring gene villin 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The coordinated action of PPR4 and EMB2654 on each intron half mediates trans-splicing of rps12 transcripts in plant chloroplasts. Lee K, et al. Plant J, 2019 Dec. PMID 31442349
  2. The Pentatricopeptide Repeat Protein EMB2654 Is Essential for Trans-Splicing of a Chloroplast Small Ribosomal Subunit Transcript. Aryamanesh N, et al. Plant Physiol, 2017 Feb. PMID 28011633, Free PMC Article
  3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The coordinated action of PPR4 and EMB2654 on each intron half mediates trans-splicing of rps12 transcripts in plant chloroplasts. Arabidopsis atppr4 and rice osppr4 mutants are embryo-lethal and seedling-lethal 3 weeks after germination, respectively, showing that PPR4 is essential in the development of both dicot and monocot plants.
    Title: The coordinated action of PPR4 and EMB2654 on each intron half mediates trans-splicing of rps12 transcripts in plant chloroplasts.
  2. EMB2654 binding must be an early step in, or prior to, the formation of a large protein-RNA complex covering the free ends of the two rps12 intron halves.
    Title: The Pentatricopeptide Repeat Protein EMB2654 Is Essential for Trans-Splicing of a Chloroplast Small Ribosomal Subunit Transcript.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001336935.1
NM_180025.2
NM_180026.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables structural constituent of ribosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within chloroplast mRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
located_in chloroplast IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Tetratricopeptide repeat (TPR)-like superfamily protein
NP_850356.1
  • EMBRYO DEFECTIVE 2654 (EMB2654); INVOLVED IN: embryo development ending in seed dormancy; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT5G02860.1); Has 63033 Blast hits to 15489 proteins in 313 species: Archae - 3; Bacteria - 71; Metazoa - 950; Fungi - 1085; Plants - 58248; Viruses - 0; Other Eukaryotes - 2676 (source: NCBI BLink).
NP_850357.2
  • EMBRYO DEFECTIVE 2654 (EMB2654); INVOLVED IN: embryo development ending in seed dormancy; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT5G02860.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    17403603..17407325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_180026.2 → NP_850357.2  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850357.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    C0Z271, F4IL02
    Conserved Domains (5) summary
    TIGR00756
    Location:435 → 468
    PPR; pentatricopeptide repeat domain (PPR motif)
    sd00004
    Location:225 → 252
    PPR; PPR repeat [structural motif]
    pfam01535
    Location:82 → 112
    PPR; PPR repeat
    pfam12854
    Location:290 → 320
    PPR_1; PPR repeat
    pfam13041
    Location:291 → 340
    PPR_2; PPR repeat family

  2. NM_180025.2 → NP_850356.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850356.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22948, Q8RWS8
    UniProtKB/TrEMBL
    A0A178VXZ9, A0A5S9X649
    Conserved Domains (3) summary
    PLN03218
    Location:190 → 606
    PLN03218; maturation of RBCL 1; Provisional
    sd00004
    Location:357 → 384
    PPR; PPR repeat [structural motif]
    pfam13041
    Location:598 → 647
    PPR_2; PPR repeat family

  3. NM_001336935.1 → NP_001323745.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VWE4, A0A1P8AXX6, A0A384LB51, C0Z271
    Conserved Domains (3) summary
    PLN03218
    Location:190 → 606
    PLN03218; maturation of RBCL 1; Provisional
    sd00004
    Location:357 → 384
    PPR; PPR repeat [structural motif]
    pfam13041
    Location:598 → 647
    PPR_2; PPR repeat family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8RWS8.1

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