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TIM triosephosphate isomerase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816652, updated on 11-Apr-2024

Summary

Gene symbol
TIM
Gene description
triosephosphate isomerase
Primary source
Araport:AT2G21170
Locus tag
AT2G21170
See related
TAIR:AT2G21170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F26H11.7; F26H11_7; PDTPI; PLASTID ISOFORM TRIOSE PHOSPHATE ISOMERASE; triosephosphate isomerase; TRIOSEPHOSPHATE ISOMERASE
Summary
Encodes a plastidic triose phosphate isomerase. Mutants with reduced pdTPI levels have difficulty transitioning from heterotrophic to autotrophic growth. The related phenotypes, such as chlorosis in light-grown seedlings may result from an accumulation of dihydroxyacetone phosphate (DHAP) and methylglyoxal (MG) in these mutants. Both splice variants appear to be expressed, but the At2g21170.2 variant appears to have a much narrower expression range limited to roots.
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Genomic context

See TIM in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Sequence:
Chromosome: 2; NC_003071.7 (9070734..9074470, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene XAP5 family protein Neighboring gene Translocon-associated protein (TRAP), alpha subunit Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001084462.1
NM_001335732.1
NM_127687.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables triose-phosphate isomerase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables triose-phosphate isomerase activity IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
triosephosphate isomerase
NP_001077931.1
  • triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: thylakoid, mitochondrion, apoplast, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11527 Blast hits to 11525 proteins in 3623 species: Archae - 144; Bacteria - 6185; Metazoa - 1204; Fungi - 240; Plants - 472; Viruses - 0; Other Eukaryotes - 3282 (source: NCBI BLink).
NP_179713.1
  • triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: in 6 components; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11587 Blast hits to 11585 proteins in 3635 species: Archae - 138; Bacteria - 6210; Metazoa - 1207; Fungi - 243; Plants - 472; Viruses - 0; Other Eukaryotes - 3317 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    9070734..9074470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127687.4NP_179713.1  triosephosphate isomerase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179713.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SKP6
    UniProtKB/TrEMBL
    A0A178VN28, A0A5S9WZU4
    Conserved Domains (1) summary
    PLN02429
    Location:1315
    PLN02429; triosephosphate isomerase
  2. NM_001335732.1NP_001323967.1  triosephosphate isomerase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SKP6
    UniProtKB/TrEMBL
    A0A178VN28, A0A5S9WZU4
    Conserved Domains (1) summary
    PLN02429
    Location:1315
    PLN02429; triosephosphate isomerase
  3. NM_001084462.1NP_001077931.1  triosephosphate isomerase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077931.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8MRE8
    Conserved Domains (1) summary
    PLN02429
    Location:1306
    PLN02429; triosephosphate isomerase