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Uck2 uridine-cytidine kinase 2 [ Mus musculus (house mouse) ]

Gene ID: 80914, updated on 12-Aug-2019

Summary

Official Symbol
Uck2provided by MGI
Official Full Name
uridine-cytidine kinase 2provided by MGI
Primary source
MGI:MGI:1931744
See related
Ensembl:ENSMUSG00000026558
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
UK; UMK; Umpk; TSA903; AA407809; AI481316; AU018180; AU020720
Expression
Ubiquitous expression in thymus adult (RPKM 18.8), CNS E11.5 (RPKM 15.9) and 28 other tissues See more
Orthologs

Genomic context

See Uck2 in Genome Data Viewer
Location:
1; 1 H2.3
Exon count:
10
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (167222895..167285933, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (169156214..169215258, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33668 Neighboring gene TSPY-like 3 pseudogene Neighboring gene predicted gene, 51816 Neighboring gene predicted gene, 46170 Neighboring gene microRNA 6347 Neighboring gene transmembrane and coiled-coil domains 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoside kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
uridine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
CMP salvage IEA
Inferred from Electronic Annotation
more info
 
UMP salvage IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
uridine-cytidine kinase 2
Names
UCK 2
cytidine monophosphokinase 2
uridine monophosphate kinase 2
uridine monophosphokinase 2
NP_109649.1
XP_006497103.1
XP_017168457.1
XP_030099584.1
XP_030099587.1
XP_030099588.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030724.3NP_109649.1  uridine-cytidine kinase 2

    See identical proteins and their annotated locations for NP_109649.1

    Status: PROVISIONAL

    Source sequence(s)
    AC142244
    Consensus CDS
    CCDS15455.1
    UniProtKB/Swiss-Prot
    Q99PM9
    UniProtKB/TrEMBL
    Q543C2
    Related
    ENSMUSP00000060202.4, ENSMUST00000053686.8
    Conserved Domains (1) summary
    cd02023
    Location:22228
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p6 C57BL/6J

    Range
    167222895..167285933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312968.2XP_017168457.1  uridine-cytidine kinase 2 isoform X5

  2. XM_030243728.1XP_030099588.1  uridine-cytidine kinase 2 isoform X4

  3. XM_030243724.1XP_030099584.1  uridine-cytidine kinase 2 isoform X1

  4. XM_006497040.4XP_006497103.1  uridine-cytidine kinase 2 isoform X2

    See identical proteins and their annotated locations for XP_006497103.1

    Conserved Domains (1) summary
    cd02023
    Location:2196
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
  5. XM_030243727.1XP_030099587.1  uridine-cytidine kinase 2 isoform X3

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