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CD36_32590 bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), putative [ Candida dubliniensis CD36 ]

Gene ID: 8049364, updated on 17-May-2024

Summary

Gene symbol
CD36_32590
Gene description
bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), putative
Locus tag
CD36_32590
See related
FungiDB:CD36_32590; VEuPathDB:CD36_32590
Gene type
protein coding
RNA name
bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), putative
RefSeq status
PROVISIONAL
Organism
Candida dubliniensis CD36 (strain: CD36)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

Location:
chromosome: R
Exon count:
1
Sequence:
Chromosome: R; NC_012867.1 (1489032..1495694, complement)

Chromosome R - NC_012867.1Genomic Context describing neighboring genes Neighboring gene pre-rRNA processing protein, putative Neighboring gene histone acetylase, putative Neighboring gene transcriptional regulator, putative Neighboring gene eukaryotic translation initiation factor, putative

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables aspartate carbamoyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables dihydroorotase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in 'de novo' pyrimidine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in UTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in citrulline biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Names
bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), putative
XP_002422215.1
  • Similar to S. cerevisiae URA2;
    includes: glutamine-dependent carbamoyl-phosphate synthase (ec 6.3.5.5); aspartate carbamoyltransferase (ec 2.1.3.2)]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012867.1 Reference assembly

    Range
    1489032..1495694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002422170.1XP_002422215.1  bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), putative [Candida dubliniensis CD36]

    See identical proteins and their annotated locations for XP_002422215.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B9WMA6
    Conserved Domains (12) summary
    cd01744
    Location:236411
    GATase1_CPSase; Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II
    COG0505
    Location:20420
    CarA; Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism, Nucleotide transport and metabolism]
    COG0540
    Location:19112218
    PyrB; Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]
    cd01423
    Location:13701491
    MGS_CPS_I_III; Methylglyoxal synthase-like domain found in pyr1 and URA1-like carbamoyl phosphate synthetases (CPS), including ammonia-dependent CPS Type I, and glutamine-dependent CPS Type III. These are multidomain proteins, in which MGS is the C-terminal domain.
    TIGR01369
    Location:4431493
    CPSaseII_lrg; carbamoyl-phosphate synthase, large subunit
    pfam00988
    Location:22160
    CPSase_sm_chain; Carbamoyl-phosphate synthase small chain, CPSase domain
    pfam02729
    Location:19182058
    OTCace_N; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
    pfam02786
    Location:565767
    CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
    pfam02787
    Location:855977
    CPSase_L_D3; Carbamoyl-phosphate synthetase large chain, oligomerization domain
    cl00281
    Location:15121832
    metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
    cl17255
    Location:11261296
    ATP-grasp_4; ATP-grasp domain
    cl21454
    Location:20652215
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins