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ATP8B4 ATPase phospholipid transporting 8B4 (putative) [ Homo sapiens (human) ]

Gene ID: 79895, updated on 25-Nov-2025
Official Symbol
ATP8B4provided by HGNC
Official Full Name
ATPase phospholipid transporting 8B4 (putative)provided by HGNC
Primary source
HGNC:HGNC:13536
See related
Ensembl:ENSG00000104043 MIM:609123; AllianceGenome:HGNC:13536
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATPIM
Summary
This gene encodes a member of the cation transport ATPase (P-type) family and type IV subfamily. The encoded protein is involved in phospholipid transport in the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Expression
Broad expression in bone marrow (RPKM 8.4), placenta (RPKM 2.4) and 14 other tissues See more
Orthologs
mouse all
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See ATP8B4 in Genome Data Viewer
Location:
15q21.2
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (49858238..50181854, complement)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (47666646..47990075, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (50150435..50411430, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9388 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr15:49917323-49918522 Neighboring gene DTW motif tRNA-uridine aminocarboxypropyltransferase 1 Neighboring gene NANOG hESC enhancer GRCh37_chr15:49990770-49991300 Neighboring gene ring finger protein, LIM domain interacting pseudogene 3 Neighboring gene uncharacterized LOC102724587 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:50201373-50201873 Neighboring gene Sharpr-MPRA regulatory region 771 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9389 Neighboring gene RNA, 5S ribosomal pseudogene 394 Neighboring gene Sharpr-MPRA regulatory region 7155 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9390 Neighboring gene NANOG hESC enhancer GRCh37_chr15:50408634-50409147 Neighboring gene ATP8B4 intron CAGE-defined high expression enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6423 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6424 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:50502954-50503533 Neighboring gene solute carrier family 27 member 2 Neighboring gene RNA, 7SL, cytoplasmic 494, pseudogene Neighboring gene histidine decarboxylase

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort. López-Isac E, et al. Arthritis Rheumatol, 2017 Jun. PMID 28141915
  2. Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing. Gao L, et al. Arthritis Rheumatol, 2016 Jan. PMID 26473621, Free PMC Article
  3. Translocation t(11;14) (q13;q32) and genomic imbalances in multi-ethnic multiple myeloma patients: a Malaysian study. Ni IB, et al. Hematol Rep, 2012 Jul 11. PMID 23087808, Free PMC Article
  4. Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells. Zhao M, et al. Oncol Rep, 2019 Mar. PMID 30664179
  5. FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body. Harris MJ, et al. Biochim Biophys Acta, 2003 Jul 21. PMID 12880872

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study did not find statistically significant differences in the frequency of the ATP8B4 rs55687265*C allele between the SSc patients and controls.
    Title: Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort.
  2. Study found that circATP8B4 in extracellular vesicles isolated from radioresistant U251 glioma cells acts as a U251 miR766 sponge, which may be involved in glioma radioresistance.
    Title: Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells.
  3. ATP8B4 gene was associated with a significant increase in the risk of systemic sclerosis. ATP8B4 is overexpressed in systemic sclerosis patients.
    Title: Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing.
  4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  5. Genome-wide association study of gene-disease association. (HuGE Navigator)
    Title: Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Submit: New GeneRIF Correction

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ25418

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled intramembrane lipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATPase-coupled intramembrane lipid transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in phospholipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phospholipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of phospholipid-translocating ATPase complex IEA
Inferred from Electronic Annotation
more info
  
part_of phospholipid-translocating ATPase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in specific granule membrane TAS
Traceable Author Statement
more info
  
located_in tertiary granule membrane TAS
Traceable Author Statement
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
probable phospholipid-transporting ATPase IM; putative phospholipid-transporting ATPase IM
Names
ATPase, class I, type 8B, member 4
P4-ATPase flippase complex alpha subunit ATP8B4
potential phospholipid-transporting ATPase IM
NP_079113.2
XP_011520348.1
XP_011520349.1
XP_011520350.1
XP_011520351.1
XP_011520354.1
XP_011520355.1
XP_011520358.3
XP_011520360.1
XP_011520361.1
XP_011520362.1
XP_011520363.1
XP_011520364.1
XP_011520365.1
XP_011520371.1
XP_011520372.1
XP_016878076.2
XP_016878080.1
XP_016878083.1
XP_024305833.1
XP_024305834.1
XP_024305835.1
XP_024305836.1
XP_024305837.1
XP_024305838.1
XP_047289038.1
XP_047289039.1
XP_047289040.1
XP_047289041.1
XP_047289042.1
XP_047289043.1
XP_047289044.1
XP_047289045.1
XP_047289046.1
XP_047289047.1
XP_047289048.1
XP_047289049.1
XP_047289050.1
XP_047289052.1
XP_047289053.1
XP_047289054.1
XP_047289055.1
XP_047289056.1
XP_054234828.1
XP_054234829.1
XP_054234830.1
XP_054234831.1
XP_054234832.1
XP_054234833.1
XP_054234834.1
XP_054234835.1
XP_054234836.1
XP_054234837.1
XP_054234838.1
XP_054234839.1
XP_054234840.1
XP_054234841.1
XP_054234842.1
XP_054234843.1
XP_054234844.1
XP_054234845.1
XP_054234846.1
XP_054234847.1
XP_054234848.1
XP_054234849.1
XP_054234850.1
XP_054234851.1
XP_054234852.1
XP_054234853.1
XP_054234854.1
XP_054234855.1
XP_054234856.1
XP_054234857.1
XP_054234858.1
XP_054234859.1
XP_054234860.1
XP_054234861.1
XP_054234862.1
XP_054234863.1
XP_054234864.1
XP_054234865.1
XP_054234866.1
XP_054234867.1
XP_054234868.1
XP_054234869.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024837.4 → NP_079113.2  probable phospholipid-transporting ATPase IM

    See identical proteins and their annotated locations for NP_079113.2

    Status: REVIEWED

    Source sequence(s)
    AC009753, BC057236, BC144297, BC144298, BE241899, BX647496
    Consensus CDS
    CCDS32238.1
    UniProtKB/Swiss-Prot
    Q8TF62, Q9H727
    Related
    ENSP00000284509.6, ENST00000284509.11
    Conserved Domains (1) summary
    cd02073
    Location:30 → 973
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

RNA

  1. NR_073596.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has an additional internal exon and lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC009753, AC016045, BC144298, BE241899, BX647496

  2. NR_073597.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC009753, BC144297, BC144298, BE241899, BX647496

  3. NR_073598.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) uses an alternate 5' exon and lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB075819, AC009753, AC016045, AC025040, BX647496
    Related
    ENST00000559726.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    49858238..50181854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011522056.4 → XP_011520358.3  putative phospholipid-transporting ATPase IM isoform X3

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  2. XM_047433096.1 → XP_047289052.1  putative phospholipid-transporting ATPase IM isoform X21

  3. XM_017022587.3 → XP_016878076.2  putative phospholipid-transporting ATPase IM isoform X6

    UniProtKB/Swiss-Prot
    Q8TF62, Q9H727
    Related
    ENSP00000565186.1, ENST00000895127.1
    Conserved Domains (1) summary
    cd02073
    Location:30 → 973
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  4. XM_047433082.1 → XP_047289038.1  putative phospholipid-transporting ATPase IM isoform X3

  5. XM_011522058.4 → XP_011520360.1  putative phospholipid-transporting ATPase IM isoform X15

    See identical proteins and their annotated locations for XP_011520360.1

    Conserved Domains (4) summary
    TIGR01652
    Location:17 → 1021
    ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase
    pfam13246
    Location:392 → 488
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16212
    Location:760 → 1014
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl21460
    Location:729 → 760
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  6. XM_047433094.1 → XP_047289050.1  putative phospholipid-transporting ATPase IM isoform X21

  7. XM_047433090.1 → XP_047289046.1  putative phospholipid-transporting ATPase IM isoform X13

  8. XM_047433088.1 → XP_047289044.1  putative phospholipid-transporting ATPase IM isoform X11

  9. XM_047433093.1 → XP_047289049.1  putative phospholipid-transporting ATPase IM isoform X19

  10. XM_047433089.1 → XP_047289045.1  putative phospholipid-transporting ATPase IM isoform X12

    Related
    ENSP00000565187.1, ENST00000895128.1

  11. XM_047433083.1 → XP_047289039.1  putative phospholipid-transporting ATPase IM isoform X6

    UniProtKB/Swiss-Prot
    Q8TF62, Q9H727
    Related
    ENSP00000565188.1, ENST00000895129.1

  12. XM_011522047.3 → XP_011520349.1  putative phospholipid-transporting ATPase IM isoform X3

    See identical proteins and their annotated locations for XP_011520349.1

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  13. XM_011522052.4 → XP_011520354.1  putative phospholipid-transporting ATPase IM isoform X3

    See identical proteins and their annotated locations for XP_011520354.1

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  14. XM_011522048.2 → XP_011520350.1  putative phospholipid-transporting ATPase IM isoform X3

    See identical proteins and their annotated locations for XP_011520350.1

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  15. XM_011522053.2 → XP_011520355.1  putative phospholipid-transporting ATPase IM isoform X3

    See identical proteins and their annotated locations for XP_011520355.1

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  16. XM_011522049.3 → XP_011520351.1  putative phospholipid-transporting ATPase IM isoform X3

    See identical proteins and their annotated locations for XP_011520351.1

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  17. XM_047433087.1 → XP_047289043.1  putative phospholipid-transporting ATPase IM isoform X10

    Related
    ENSP00000636612.1, ENST00000966553.1

  18. XM_047433084.1 → XP_047289040.1  putative phospholipid-transporting ATPase IM isoform X7

  19. XM_047433091.1 → XP_047289047.1  putative phospholipid-transporting ATPase IM isoform X14

  20. XM_047433085.1 → XP_047289041.1  putative phospholipid-transporting ATPase IM isoform X8

  21. XM_047433086.1 → XP_047289042.1  putative phospholipid-transporting ATPase IM isoform X9

  22. XM_024450065.2 → XP_024305833.1  putative phospholipid-transporting ATPase IM isoform X2

    Conserved Domains (1) summary
    cd02073
    Location:67 → 1010
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  23. XM_024450066.2 → XP_024305834.1  putative phospholipid-transporting ATPase IM isoform X4

    Conserved Domains (1) summary
    cd02073
    Location:67 → 985
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  24. XM_024450067.2 → XP_024305835.1  putative phospholipid-transporting ATPase IM isoform X5

    Conserved Domains (1) summary
    cd02073
    Location:67 → 975
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  25. XM_011522046.3 → XP_011520348.1  putative phospholipid-transporting ATPase IM isoform X1

    Conserved Domains (5) summary
    TIGR01652
    Location:65 → 1167
    ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase
    pfam13246
    Location:538 → 634
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16209
    Location:51 → 116
    PhoLip_ATPase_N; Phospholipid-translocating ATPase N-terminal
    pfam16212
    Location:906 → 1160
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl21460
    Location:875 → 906
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  26. XM_017022591.2 → XP_016878080.1  putative phospholipid-transporting ATPase IM isoform X3

    Conserved Domains (1) summary
    cd02073
    Location:30 → 1001
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  27. XM_047433092.1 → XP_047289048.1  putative phospholipid-transporting ATPase IM isoform X18

  28. XM_017022594.1 → XP_016878083.1  putative phospholipid-transporting ATPase IM isoform X15

    Conserved Domains (4) summary
    TIGR01652
    Location:17 → 1021
    ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase
    pfam13246
    Location:392 → 488
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16212
    Location:760 → 1014
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl21460
    Location:729 → 760
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  29. XM_011522059.1 → XP_011520361.1  putative phospholipid-transporting ATPase IM isoform X16

    Conserved Domains (4) summary
    TIGR01652
    Location:11 → 1015
    ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase
    pfam13246
    Location:386 → 482
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16212
    Location:754 → 1008
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl21460
    Location:723 → 754
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  30. XM_011522061.1 → XP_011520363.1  putative phospholipid-transporting ATPase IM isoform X17

    See identical proteins and their annotated locations for XP_011520363.1

    Conserved Domains (1) summary
    cd02073
    Location:2 → 874
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  31. XM_011522060.1 → XP_011520362.1  putative phospholipid-transporting ATPase IM isoform X17

    See identical proteins and their annotated locations for XP_011520362.1

    Conserved Domains (1) summary
    cd02073
    Location:2 → 874
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  32. XM_047433098.1 → XP_047289054.1  putative phospholipid-transporting ATPase IM isoform X23

  33. XM_011522062.1 → XP_011520364.1  putative phospholipid-transporting ATPase IM isoform X17

    See identical proteins and their annotated locations for XP_011520364.1

    Conserved Domains (1) summary
    cd02073
    Location:2 → 874
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  34. XM_011522063.1 → XP_011520365.1  putative phospholipid-transporting ATPase IM isoform X17

    See identical proteins and their annotated locations for XP_011520365.1

    Conserved Domains (1) summary
    cd02073
    Location:2 → 874
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  35. XM_047433097.1 → XP_047289053.1  putative phospholipid-transporting ATPase IM isoform X23

  36. XM_024450069.1 → XP_024305837.1  putative phospholipid-transporting ATPase IM isoform X22

    Conserved Domains (1) summary
    cd02073
    Location:7 → 789
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  37. XM_011522069.2 → XP_011520371.1  putative phospholipid-transporting ATPase IM isoform X24

    See identical proteins and their annotated locations for XP_011520371.1

    Conserved Domains (5) summary
    COG0474
    Location:1 → 799
    MgtA; Magnesium-transporting ATPase (P-type) [Inorganic ion transport and metabolism]
    TIGR01484
    Location:396 → 577
    HAD-SF-IIB; HAD-superfamily hydrolase, subfamily IIB
    pfam13246
    Location:218 → 314
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16212
    Location:586 → 840
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl21460
    Location:555 → 586
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  38. XM_011522070.2 → XP_011520372.1  putative phospholipid-transporting ATPase IM isoform X27

    Conserved Domains (5) summary
    COG0474
    Location:7 → 601
    MgtA; Magnesium-transporting ATPase (P-type) [Inorganic ion transport and metabolism]
    TIGR01484
    Location:198 → 379
    HAD-SF-IIB; HAD-superfamily hydrolase, subfamily IIB
    pfam13246
    Location:20 → 116
    Cation_ATPase; Cation transport ATPase (P-type)
    pfam16212
    Location:388 → 642
    PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
    cl21460
    Location:357 → 388
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  39. XM_024450068.2 → XP_024305836.1  putative phospholipid-transporting ATPase IM isoform X20

    Conserved Domains (1) summary
    cd02073
    Location:67 → 1038
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

  40. XM_047433099.1 → XP_047289055.1  putative phospholipid-transporting ATPase IM isoform X25

  41. XM_047433100.1 → XP_047289056.1  putative phospholipid-transporting ATPase IM isoform X26

    UniProtKB/TrEMBL
    H0YMP8
    Related
    ENSP00000453690.1, ENST00000557955.5

  42. XM_024450070.2 → XP_024305838.1  putative phospholipid-transporting ATPase IM isoform X28

    UniProtKB/TrEMBL
    H0YMP8
    Conserved Domains (1) summary
    cd02073
    Location:67 → 706
    P-type_ATPase_APLT_Dnf-like; Aminophospholipid translocases (APLTs), similar to Saccharomyces cerevisiae Dnf1-3p, Drs2p, and human ATP8A2, -10D, -11B, -11C

RNA

  1. XR_002957687.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    47666646..47990075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054378873.1 → XP_054234848.1  putative phospholipid-transporting ATPase IM isoform X3

  2. XM_054378886.1 → XP_054234861.1  putative phospholipid-transporting ATPase IM isoform X21

  3. XM_054378865.1 → XP_054234840.1  putative phospholipid-transporting ATPase IM isoform X6

  4. XM_054378860.1 → XP_054234835.1  putative phospholipid-transporting ATPase IM isoform X3

  5. XM_054378857.1 → XP_054234832.1  putative phospholipid-transporting ATPase IM isoform X3

  6. XM_054378876.1 → XP_054234851.1  putative phospholipid-transporting ATPase IM isoform X15

  7. XM_054378870.1 → XP_054234845.1  putative phospholipid-transporting ATPase IM isoform X11

  8. XM_054378885.1 → XP_054234860.1  putative phospholipid-transporting ATPase IM isoform X21

  9. XM_054378872.1 → XP_054234847.1  putative phospholipid-transporting ATPase IM isoform X13

  10. XM_054378883.1 → XP_054234858.1  putative phospholipid-transporting ATPase IM isoform X19

  11. XM_054378871.1 → XP_054234846.1  putative phospholipid-transporting ATPase IM isoform X12

  12. XM_054378864.1 → XP_054234839.1  putative phospholipid-transporting ATPase IM isoform X6

  13. XM_054378859.1 → XP_054234834.1  putative phospholipid-transporting ATPase IM isoform X3

  14. XM_054378858.1 → XP_054234833.1  putative phospholipid-transporting ATPase IM isoform X3

  15. XM_054378855.1 → XP_054234830.1  putative phospholipid-transporting ATPase IM isoform X3

  16. XM_054378856.1 → XP_054234831.1  putative phospholipid-transporting ATPase IM isoform X3

  17. XM_054378869.1 → XP_054234844.1  putative phospholipid-transporting ATPase IM isoform X10

  18. XM_054378866.1 → XP_054234841.1  putative phospholipid-transporting ATPase IM isoform X7

  19. XM_054378874.1 → XP_054234849.1  putative phospholipid-transporting ATPase IM isoform X14

  20. XM_054378867.1 → XP_054234842.1  putative phospholipid-transporting ATPase IM isoform X8

  21. XM_054378868.1 → XP_054234843.1  putative phospholipid-transporting ATPase IM isoform X9

  22. XM_054378854.1 → XP_054234829.1  putative phospholipid-transporting ATPase IM isoform X2

  23. XM_054378862.1 → XP_054234837.1  putative phospholipid-transporting ATPase IM isoform X4

  24. XM_054378863.1 → XP_054234838.1  putative phospholipid-transporting ATPase IM isoform X5

  25. XM_054378853.1 → XP_054234828.1  putative phospholipid-transporting ATPase IM isoform X1

  26. XM_054378861.1 → XP_054234836.1  putative phospholipid-transporting ATPase IM isoform X3

  27. XM_054378882.1 → XP_054234857.1  putative phospholipid-transporting ATPase IM isoform X18

  28. XM_054378875.1 → XP_054234850.1  putative phospholipid-transporting ATPase IM isoform X15

  29. XM_054378877.1 → XP_054234852.1  putative phospholipid-transporting ATPase IM isoform X16

  30. XM_054378879.1 → XP_054234854.1  putative phospholipid-transporting ATPase IM isoform X17

  31. XM_054378878.1 → XP_054234853.1  putative phospholipid-transporting ATPase IM isoform X17

  32. XM_054378889.1 → XP_054234864.1  putative phospholipid-transporting ATPase IM isoform X23

  33. XM_054378880.1 → XP_054234855.1  putative phospholipid-transporting ATPase IM isoform X17

  34. XM_054378881.1 → XP_054234856.1  putative phospholipid-transporting ATPase IM isoform X17

  35. XM_054378888.1 → XP_054234863.1  putative phospholipid-transporting ATPase IM isoform X23

  36. XM_054378887.1 → XP_054234862.1  putative phospholipid-transporting ATPase IM isoform X22

  37. XM_054378890.1 → XP_054234865.1  putative phospholipid-transporting ATPase IM isoform X24

  38. XM_054378893.1 → XP_054234868.1  putative phospholipid-transporting ATPase IM isoform X27

  39. XM_054378884.1 → XP_054234859.1  putative phospholipid-transporting ATPase IM isoform X20

  40. XM_054378891.1 → XP_054234866.1  putative phospholipid-transporting ATPase IM isoform X25

  41. XM_054378892.1 → XP_054234867.1  putative phospholipid-transporting ATPase IM isoform X26

    UniProtKB/TrEMBL
    H0YMP8

  42. XM_054378894.1 → XP_054234869.1  putative phospholipid-transporting ATPase IM isoform X28

    UniProtKB/TrEMBL
    H0YMP8

RNA

  1. XR_008489011.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8TF62.3 GenPept UniProtKB/Swiss-Prot:Q8TF62

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