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MFSD13A major facilitator superfamily domain containing 13A [ Homo sapiens (human) ]

Gene ID: 79847, updated on 22-Sep-2022

Summary

Official Symbol
MFSD13Aprovided by HGNC
Official Full Name
major facilitator superfamily domain containing 13Aprovided by HGNC
Primary source
HGNC:HGNC:26196
See related
Ensembl:ENSG00000138111 AllianceGenome:HGNC:26196
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TMEM180; C10orf77; bA18I14.8
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in brain (RPKM 9.0), lung (RPKM 6.4) and 25 other tissues See more
Orthologs
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Genomic context

See MFSD13A in Genome Data Viewer
Location:
10q24.32
Exon count:
16
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (102461395..102477045)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (103346383..103362022)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (104221152..104236802)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene C10orf95 antisense RNA 1 Neighboring gene microRNA 146b Neighboring gene chromosome 10 open reading frame 95 Neighboring gene uncharacterized LOC124902493 Neighboring gene actin related protein 1A Neighboring gene Sharpr-MPRA regulatory region 236 Neighboring gene SUFU negative regulator of hedgehog signaling

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

EBI GWAS Catalog

Description
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22529

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024789.4NP_079065.2  transmembrane protein 180

    See identical proteins and their annotated locations for NP_079065.2

    Status: VALIDATED

    Source sequence(s)
    AL121928, BC057787, BG830198
    Consensus CDS
    CCDS7535.1
    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Related
    ENSP00000238936.3, ENST00000238936.8
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    102461395..102477045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540160.3XP_011538462.1  transmembrane protein 180 isoform X1

    See identical proteins and their annotated locations for XP_011538462.1

    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein
  2. XM_006717973.4XP_006718036.1  transmembrane protein 180 isoform X1

    See identical proteins and their annotated locations for XP_006718036.1

    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein
  3. XM_024448171.2XP_024303939.1  transmembrane protein 180 isoform X2

  4. XM_011540163.3XP_011538465.1  transmembrane protein 180 isoform X1

    See identical proteins and their annotated locations for XP_011538465.1

    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein
  5. XM_047425757.1XP_047281713.1  transmembrane protein 180 isoform X2

  6. XM_017016654.2XP_016872143.1  transmembrane protein 180 isoform X1

    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein
  7. XM_047425756.1XP_047281712.1  transmembrane protein 180 isoform X2

  8. XM_047425755.1XP_047281711.1  transmembrane protein 180 isoform X2

  9. XM_006717974.4XP_006718037.1  transmembrane protein 180 isoform X1

    See identical proteins and their annotated locations for XP_006718037.1

    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein
  10. XM_011540167.3XP_011538469.1  transmembrane protein 180 isoform X2

    See identical proteins and their annotated locations for XP_011538469.1

  11. XM_017016661.2XP_016872150.1  transmembrane protein 180 isoform X3

    Conserved Domains (1) summary
    cl26210
    Location:23276
    MFS_2; MFS/sugar transport protein
  12. XM_017016662.2XP_016872151.1  transmembrane protein 180 isoform X3

    Conserved Domains (1) summary
    cl26210
    Location:23276
    MFS_2; MFS/sugar transport protein
  13. XM_047425759.1XP_047281715.1  transmembrane protein 180 isoform X3

  14. XM_024448172.2XP_024303940.1  transmembrane protein 180 isoform X3

    Conserved Domains (1) summary
    cl26210
    Location:23276
    MFS_2; MFS/sugar transport protein
  15. XM_047425751.1XP_047281707.1  transmembrane protein 180 isoform X1

    UniProtKB/Swiss-Prot
    Q9H679
  16. XM_047425753.1XP_047281709.1  transmembrane protein 180 isoform X1

    UniProtKB/Swiss-Prot
    Q9H679
  17. XM_017016655.1XP_016872144.1  transmembrane protein 180 isoform X1

    UniProtKB/Swiss-Prot
    Q14CX5, Q9H679
    Conserved Domains (1) summary
    cl26210
    Location:23426
    MFS_2; MFS/sugar transport protein
  18. XM_047425752.1XP_047281708.1  transmembrane protein 180 isoform X1

    UniProtKB/Swiss-Prot
    Q9H679
  19. XM_047425758.1XP_047281714.1  transmembrane protein 180 isoform X2

  20. XM_047425754.1XP_047281710.1  transmembrane protein 180 isoform X1

    UniProtKB/Swiss-Prot
    Q9H679
  21. XM_047425760.1XP_047281716.1  transmembrane protein 180 isoform X4

    UniProtKB/TrEMBL
    B4DKJ1
  22. XM_047425761.1XP_047281717.1  transmembrane protein 180 isoform X4

    UniProtKB/TrEMBL
    B4DKJ1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    103346383..103362022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)