KLF3-AS1 KLF3 antisense RNA 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: KLF3-AS1provided by HGNC
Official Full Name: KLF3 antisense RNA 1provided by HGNC
Primary source: HGNC:HGNC:25796
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression: Ubiquitous expression in ovary (RPKM 5.9), endometrium (RPKM 4.7) and 25 other tissues See more

Genomic context

Location:: 4p14

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
109.20200522	current	GRCh38.p13 (GCF_000001405.39)	4	NC_000004.12 (38612701..38664628, complement)
105	previous assembly	GRCh37.p13 (GCF_000001405.25)	4	NC_000004.11 (38614322..38666581, complement)

Chromosome 4 - NC_000004.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Exosomal KLF3-AS1 derived from mesenchymal stem cells is involved in MSC-exosome-mediated chondrocyte proliferation induction and chondrocyte apoptosis inhibition via miR-206/GIT1 axis.
Title: MSC-derived exosomes promote proliferation and inhibit apoptosis of chondrocytes via lncRNA-KLF3-AS1/miR-206/GIT1 axis in osteoarthritis.

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

D4S744 (e-PCR)
- UniSTS:4869

REN36941 (e-PCR)
- UniSTS:361741

D1S1425 (e-PCR)
- UniSTS:149621

NoName (e-PCR)
- UniSTS:484743

D1S1459 (e-PCR)
- UniSTS:149655

SHGC-153605 (e-PCR)
- UniSTS:177837

G31615 (e-PCR)
- UniSTS:77287

SHGC-67372 (e-PCR)
- UniSTS:47603

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_026804.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC021860

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

NC_000004.12 Reference GRCh38.p13 Primary Assembly

Range

38612701..38664628 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_024614.1: Suppressed sequence

Description

NM_024614.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.