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OGFRL1 opioid growth factor receptor like 1 [ Homo sapiens (human) ]

Gene ID: 79627, updated on 24-Nov-2020

Summary

Official Symbol
OGFRL1provided by HGNC
Official Full Name
opioid growth factor receptor like 1provided by HGNC
Primary source
HGNC:HGNC:21378
See related
Ensembl:ENSG00000119900
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
dJ331H24.1
Expression
Ubiquitous expression in brain (RPKM 22.5), esophagus (RPKM 15.1) and 24 other tissues See more
Orthologs

Genomic context

See OGFRL1 in Genome Data Viewer
Location:
6q13
Exon count:
12
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (71288296..71309059)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (71998477..72013267)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 411, pseudogene Neighboring gene coiled-coil domain containing 112 pseudogene Neighboring gene origin of replication 343 Neighboring gene microRNA 30c-2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21079, MGC102783

Gene Ontology Provided by GOA

Function Evidence Code Pubs
opioid receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
opioid receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
opioid growth factor receptor-like protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001324266.2NP_001311195.1  opioid growth factor receptor-like protein 1 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AI800853, AK124833, AK308623, AL137346, BC018688, BX379107, BX420584, BX488500, CK819012, DA151056, DA330565, DA852679
    UniProtKB/Swiss-Prot
    Q5TC84
    Conserved Domains (2) summary
    pfam04664
    Location:114320
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
    cl15483
    Location:254434
    Hid1; High-temperature-induced dauer-formation protein
  2. NM_024576.5NP_078852.3  opioid growth factor receptor-like protein 1 isoform b

    See identical proteins and their annotated locations for NP_078852.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a.
    Source sequence(s)
    AI800853, AK124833, AK308623, AL137346, BC018688, BX488500, CK819012, DA151056, DA330565, DA852679
    Consensus CDS
    CCDS34482.1
    UniProtKB/Swiss-Prot
    Q5TC84
    Related
    ENSP00000359464.3, ENST00000370435.5
    Conserved Domains (2) summary
    pfam04664
    Location:113319
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
    cl15483
    Location:253433
    Hid1; High-temperature-induced dauer-formation protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    71288296..71309059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017011303.1XP_016866792.1  opioid growth factor receptor-like protein 1 isoform X1

  2. XM_017011304.1XP_016866793.1  opioid growth factor receptor-like protein 1 isoform X2

  3. XM_017011305.2XP_016866794.1  opioid growth factor receptor-like protein 1 isoform X3

  4. XM_011536118.2XP_011534420.1  opioid growth factor receptor-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_011534420.1

    UniProtKB/Swiss-Prot
    Q5TC84
    Conserved Domains (2) summary
    pfam04664
    Location:1120
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
    cl15483
    Location:54234
    Hid1; High-temperature-induced dauer-formation protein
  5. XM_017011306.2XP_016866795.1  opioid growth factor receptor-like protein 1 isoform X4

    UniProtKB/Swiss-Prot
    Q5TC84
    Related
    ENSP00000496790.1, ENST00000650315.1
    Conserved Domains (2) summary
    pfam04664
    Location:1120
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
    cl15483
    Location:54234
    Hid1; High-temperature-induced dauer-formation protein
  6. XM_011536117.2XP_011534419.1  opioid growth factor receptor-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_011534419.1

    UniProtKB/Swiss-Prot
    Q5TC84
    Conserved Domains (2) summary
    pfam04664
    Location:1120
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
    cl15483
    Location:54234
    Hid1; High-temperature-induced dauer-formation protein
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