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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_030378.1 RefSeqGene
- Range
-
5099..7731
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001166538.1 → NP_001160010.1 leukocyte-specific transcript 1 protein isoform 6
See identical proteins and their annotated locations for NP_001160010.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (6) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because the transcripts supporting this CDS exon combination lack a complete 5' UTR, and alternative splicing choices exist further upstream.
- Source sequence(s)
-
AI091696, Y18486
- Consensus CDS
-
CCDS54987.1
- UniProtKB/Swiss-Prot
-
O00453
- Related
- ENSP00000365254.3, ENST00000376086.7
- Conserved Domains (1) summary
-
- pfam05083
Location:7 → 72
- LST1; LST-1 protein
-
NM_007161.3 → NP_009092.3 leukocyte-specific transcript 1 protein isoform 1
See identical proteins and their annotated locations for NP_009092.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1). The 5' UTR of this variant is incomplete because the transcripts supporting this CDS exon combination lack a complete 5' UTR, and alternative splicing choices exist further upstream.
- Source sequence(s)
-
AI091696, AL662801, AV715235, AY852266
- Consensus CDS
-
CCDS54984.1
- UniProtKB/Swiss-Prot
-
O00453
- Related
- ENSP00000365261.2, ENST00000376093.6
- Conserved Domains (1) summary
-
- pfam05083
Location:28 → 103
- LST1; LST-1 protein
-
NM_205837.3 → NP_995309.2 leukocyte-specific transcript 1 protein isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) includes an additional exon in the 5' UTR and lacks an internal exon that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AF000424, AI091696
- Consensus CDS
-
CCDS54985.1
- UniProtKB/Swiss-Prot
-
O00453
- Related
- ENSP00000339201.4, ENST00000339530.8
-
NM_205838.3 → NP_995310.2 leukocyte-specific transcript 1 protein isoform 3
See identical proteins and their annotated locations for NP_995310.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) includes an additional exon in the 5' UTR, lacks an alternate in-frame exon in the 5' coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AI091696, AV715235
- Consensus CDS
-
CCDS4705.2
- UniProtKB/Swiss-Prot
-
O00453
- Related
- ENSP00000405900.2, ENST00000418507.6
- Conserved Domains (1) summary
-
- pfam05083
Location:7 → 65
- LST1; LST-1 protein
-
NM_205839.3 → NP_995311.2 leukocyte-specific transcript 1 protein isoform 4
See identical proteins and their annotated locations for NP_995311.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) includes an additional exon in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
- Source sequence(s)
-
AF000425, AI091696, AL662801
- Consensus CDS
-
CCDS43450.2
- UniProtKB/Swiss-Prot
- O00453, Q9UJS1
- UniProtKB/TrEMBL
-
A0A024RCT6
- Related
- ENSP00000391929.3, ENST00000438075.7
- Conserved Domains (1) summary
-
- pfam05083
Location:28 → 96
- LST1; LST-1 protein
-
NM_205840.2 → NP_995312.2 leukocyte-specific transcript 1 protein isoform 5
See identical proteins and their annotated locations for NP_995312.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an alternate exon in the central coding region and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (5) has a distinct C-terminus and is shorter than isoform 1. The 5' UTR of this variant is incomplete because the transcripts supporting this CDS exon combination lack a complete 5' UTR, and alternative splicing choices exist further upstream.
- Source sequence(s)
-
AI091696, Y18487
- Consensus CDS
-
CCDS54986.1
- UniProtKB/Swiss-Prot
-
O00453
- Related
- ENSP00000303649.7, ENST00000303757.12
RNA
-
NR_029461.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) includes an additional 5' exon, lacks two alternate internal exons, and uses an alternate splice site in the 3' terminal exon, compared to variant 1. This variant is represented as non-coding due to uncertainty about its protein-coding capacity; only a very short protein would result from translation initiation at the supported start codon, as used by variant 1.
- Source sequence(s)
-
AI091696, AJ705986
- Related
-
ENST00000376099.5
-
NR_029462.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) includes an additional 5' exon, lacks two alternate internal exons, and uses an alternate splice site in the 3' terminal exon, compared to variant 1. This variant is represented as non-coding due to uncertainty about its protein-coding capacity; only a very short protein would result from translation initiation at the supported start codon, as used by variant 1.
- Source sequence(s)
-
AI091696, AV711621
- Related
-
ENST00000376096.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000006.12 Reference GRCh38.p14 Primary Assembly
- Range
-
31586277..31588909
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006715206.4 → XP_006715269.1 leukocyte-specific transcript 1 protein isoform X1
See identical proteins and their annotated locations for XP_006715269.1
- UniProtKB/Swiss-Prot
-
O00453
- Conserved Domains (1) summary
-
- pfam05083
Location:28 → 103
- LST1; LST-1 protein
-
XM_006715210.4 → XP_006715273.1 leukocyte-specific transcript 1 protein isoform X4
See identical proteins and their annotated locations for XP_006715273.1
- UniProtKB/Swiss-Prot
-
O00453
-
XM_006715209.4 → XP_006715272.1 leukocyte-specific transcript 1 protein isoform X3
See identical proteins and their annotated locations for XP_006715272.1
- UniProtKB/Swiss-Prot
-
O00453
- Conserved Domains (1) summary
-
- pfam05083
Location:7 → 72
- LST1; LST-1 protein
-
XM_011514914.3 → XP_011513216.1 leukocyte-specific transcript 1 protein isoform X1
See identical proteins and their annotated locations for XP_011513216.1
- UniProtKB/Swiss-Prot
-
O00453
- Conserved Domains (1) summary
-
- pfam05083
Location:28 → 103
- LST1; LST-1 protein
-
XM_047419357.1 → XP_047275313.1 leukocyte-specific transcript 1 protein isoform X2
- UniProtKB/Swiss-Prot
-
Q9UJS1
- UniProtKB/TrEMBL
-
A0A024RCT6
Reference GRCh38.p14 ALT_REF_LOCI_1
Genomic
-
NT_167244.2 Reference GRCh38.p14 ALT_REF_LOCI_1
- Range
-
2918856..2921488
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_2
Genomic
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NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2
- Range
-
3063564..3066192
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_3
Genomic
-
NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3
- Range
-
2834012..2836646
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_4
Genomic
-
NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4
- Range
-
2891318..2893950
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_5
Genomic
-
NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5
- Range
-
2928172..2930802
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_6
Genomic
-
NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6
- Range
-
2842098..2844732
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_7
Genomic
-
NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7
- Range
-
2885558..2888190
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060930.1 Alternate T2T-CHM13v2.0
- Range
-
31439327..31441957
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)