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Snrnp25 small nuclear ribonucleoprotein 25 (U11/U12) [ Mus musculus (house mouse) ]

Gene ID: 78372, updated on 2-Nov-2024

Summary

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Official Symbol
Snrnp25provided by MGI
Official Full Name
small nuclear ribonucleoprotein 25 (U11/U12)provided by MGI
Primary source
MGI:MGI:1925622
See related
Ensembl:ENSMUSG00000040767 AllianceGenome:MGI:1925622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C16ORF33; 3300001G02Rik
Summary
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be part of U12-type spliceosomal complex. Is expressed in testis. Orthologous to human SNRNP25 (small nuclear ribonucleoprotein U11/U12 subunit 25). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in liver E14 (RPKM 36.3), liver E14.5 (RPKM 34.3) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Snrnp25 in Genome Data Viewer
Location:
11 A4; 11 18.82 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (32155415..32158996)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (32205415..32208996)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40823 Neighboring gene predicted gene 12109 Neighboring gene interleukin 9 receptor Neighboring gene STARR-positive B cell enhancer ABC_E730 Neighboring gene STARR-positive B cell enhancer ABC_E11473 Neighboring gene rhomboid 5 homolog 1 Neighboring gene alpha-globin locus regulatory region Neighboring gene N-methylpurine-DNA glycosylase Neighboring gene nitrogen permease regulator-like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Flint J, et al. Hum Mol Genet, 2001 Feb 15. PMID 11157800
  2. Minor spliceosome components are predominantly localized in the nucleus. Pessa HK, et al. Proc Natl Acad Sci U S A, 2008 Jun 24. PMID 18559850, Free PMC Article
  3. Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis. O'Shaughnessy PJ, et al. Endocrinology, 2007 Jun. PMID 17332066
  4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
  5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
  
part_of U12-type spliceosomal complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in intercellular bridge ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
U11/U12 small nuclear ribonucleoprotein 25 kDa protein
Names
U11/U12 snRNP 25 kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030093.3 → NP_084369.2  U11/U12 small nuclear ribonucleoprotein 25 kDa protein

    See identical proteins and their annotated locations for NP_084369.2

    Status: VALIDATED

    Source sequence(s)
    AA199179, AK019452, BC028766
    Consensus CDS
    CCDS24518.1
    UniProtKB/Swiss-Prot
    Q8VIK1, Q9CX75
    Related
    ENSMUSP00000046654.4, ENSMUST00000039601.10
    Conserved Domains (1) summary
    cd17058
    Location:31 → 119
    Ubl_SNRNP25; ubiquitin-like (Ubl) domain found in small nuclear ribonucleoprotein U11/U12 subunit 25 (SNRNP25) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    32155415..32158996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VIK1.1 GenPept UniProtKB/Swiss-Prot:Q8VIK1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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