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Shisa4 shisa family member 4 [ Mus musculus (house mouse) ]

Gene ID: 77552, updated on 12-May-2024

Summary

Official Symbol
Shisa4provided by MGI
Official Full Name
shisa family member 4provided by MGI
Primary source
MGI:MGI:1924802
See related
Ensembl:ENSMUSG00000041889 AllianceGenome:MGI:1924802
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tmem58; mShisa4; 9330132O05Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including eye; gut; limb; male reproductive gland or organ; and nervous system. Orthologous to human SHISA4 (shisa family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 47.1), frontal lobe adult (RPKM 41.4) and 18 other tissues See more
Orthologs
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Genomic context

See Shisa4 in Genome Data Viewer
Location:
1 E4; 1 58.58 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (135298578..135302812, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (135371057..135375298, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02362 Neighboring gene predicted gene, 41956 Neighboring gene leiomodin 1 (smooth muscle) Neighboring gene STARR-seq mESC enhancer starr_02364 Neighboring gene STARR-seq mESC enhancer starr_02365 Neighboring gene importin 9 Neighboring gene STARR-positive B cell enhancer ABC_E10038 Neighboring gene neuron navigator 1 Neighboring gene microRNA 1231

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General protein information

Preferred Names
protein shisa-4
Names
shisa homolog 4
transmembrane protein 58

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175259.5NP_780468.1  protein shisa-4 precursor

    See identical proteins and their annotated locations for NP_780468.1

    Status: VALIDATED

    Source sequence(s)
    AC016814
    Consensus CDS
    CCDS15319.1
    UniProtKB/Swiss-Prot
    Q8CA71
    Related
    ENSMUSP00000046033.4, ENSMUST00000041240.4
    Conserved Domains (1) summary
    pfam13908
    Location:29178
    Shisa; Wnt and FGF inhibitory regulator

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    135298578..135302812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)