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Ankrd55 ankyrin repeat domain 55 [ Mus musculus (house mouse) ]

Gene ID: 77318, updated on 2-Nov-2024

Summary

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Official Symbol
Ankrd55provided by MGI
Official Full Name
ankyrin repeat domain 55provided by MGI
Primary source
MGI:MGI:1924568
See related
Ensembl:ENSMUSG00000049985 AllianceGenome:MGI:1924568
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C030011J08Rik
Summary
Is expressed in limb. Orthologous to human ANKRD55 (ankyrin repeat domain 55). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 1.5), cerebellum adult (RPKM 1.1) and 12 other tissues See more
Orthologs
human all
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Genomic context

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See Ankrd55 in Genome Data Viewer
Location:
13 D2.2; 13 63.73 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (112424985..112523391)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (112288451..112384005)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35683 Neighboring gene predicted gene, 33849 Neighboring gene STARR-seq mESC enhancer starr_35685 Neighboring gene predicted gene, 53816 Neighboring gene STARR-positive B cell enhancer ABC_E7287 Neighboring gene STARR-seq mESC enhancer starr_35687 Neighboring gene predicted gene, 41065 Neighboring gene predicted gene, 48837 Neighboring gene STARR-positive B cell enhancer mm9_chr13:113188373-113188674 Neighboring gene STARR-seq mESC enhancer starr_35690 Neighboring gene STARR-seq mESC enhancer starr_35691 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:113214843-113215211 Neighboring gene predicted gene, 33905 Neighboring gene STARR-positive B cell enhancer mm9_chr13:113223673-113223974 Neighboring gene STARR-positive B cell enhancers ABC_E5418 and ABC_E4097 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:113229709-113229897 Neighboring gene STARR-positive B cell enhancer ABC_E1890 Neighboring gene STARR-positive B cell enhancer ABC_E8545 Neighboring gene STARR-seq mESC enhancer starr_35693 Neighboring gene interleukin 6 signal transducer

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 55

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168403.1 → NP_001161875.1  ankyrin repeat domain-containing protein 55 isoform 2

    See identical proteins and their annotated locations for NP_001161875.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an additional exon in the 5' region, as compared to variant 1. This results in a downstream AUG start codon and the resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1.
    Source sequence(s)
    AK021066, AK039553, AK045480, AK140417
    Consensus CDS
    CCDS49365.1
    UniProtKB/TrEMBL
    A7MCU1, E9Q0E9
    Related
    ENSMUSP00000126199.2, ENSMUST00000165593.9
    Conserved Domains (2) summary
    PHA03095
    Location:3 → 286
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:64 → 95
    ANK; ANK repeat [structural motif]

  2. NM_001168404.1 → NP_001161876.1  ankyrin repeat domain-containing protein 55 isoform 3

    See identical proteins and their annotated locations for NP_001161876.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has a split 5' exon and lacks several 3' exons but has an alternate 3' segment, as compared to variant 1. The resulting isoform (3) is much shorter and has a different C-terminus, as compared to isoform 1.
    Source sequence(s)
    AK081197
    Consensus CDS
    CCDS49364.1
    UniProtKB/TrEMBL
    Q8BV14
    Related
    ENSMUSP00000129726.2, ENSMUST00000168684.2
    Conserved Domains (4) summary
    cd00204
    Location:120 → 249
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:97 → 191
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:196 → 249
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:92 → 123
    ANK; ANK repeat [structural motif]

  3. NM_001168405.1 → NP_001161877.1  ankyrin repeat domain-containing protein 55 isoform 4

    See identical proteins and their annotated locations for NP_001161877.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks multiple 3' exons but has an alternate 3' exon, as compared to variant 1. The resulting isoform (4) is much shorter and has a different C-terminus, as compared to isoform 1.
    Source sequence(s)
    AK039553
    Consensus CDS
    CCDS49363.1
    UniProtKB/TrEMBL
    Q8BYH9
    Related
    ENSMUSP00000058891.8, ENSMUST00000056047.14
    Conserved Domains (3) summary
    cd00204
    Location:33 → 146
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:31 → 123
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:59 → 90
    ANK; ANK repeat [structural motif]

  4. NM_029898.3 → NP_084174.2  ankyrin repeat domain-containing protein 55 isoform 1

    See identical proteins and their annotated locations for NP_084174.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AK021066, AK039553, AK045480, AK138273, BC152317
    Consensus CDS
    CCDS26772.1
    UniProtKB/Swiss-Prot
    E9QPX4, Q3UUM0, Q8BLD6, Q9CTM6
    UniProtKB/TrEMBL
    A7MCU1
    Related
    ENSMUSP00000022275.7, ENSMUST00000022275.14
    Conserved Domains (2) summary
    PHA03095
    Location:20 → 314
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:92 → 123
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    112424985..112523391
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158223.1 → XP_036014116.1  ankyrin repeat domain-containing protein 55 isoform X3

    Conserved Domains (2) summary
    PHA03095
    Location:20 → 314
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:92 → 123
    ANK; ANK repeat [structural motif]

  2. XM_006517789.4 → XP_006517852.1  ankyrin repeat domain-containing protein 55 isoform X1

    See identical proteins and their annotated locations for XP_006517852.1

    UniProtKB/Swiss-Prot
    E9QPX4, Q3UUM0, Q8BLD6, Q9CTM6
    UniProtKB/TrEMBL
    A7MCU1
    Conserved Domains (2) summary
    PHA03095
    Location:20 → 314
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:92 → 123
    ANK; ANK repeat [structural motif]

  3. XM_017315640.3 → XP_017171129.1  ankyrin repeat domain-containing protein 55 isoform X6

    Conserved Domains (2) summary
    PHA03095
    Location:20 → 314
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:92 → 123
    ANK; ANK repeat [structural motif]

  4. XM_036158222.1 → XP_036014115.1  ankyrin repeat domain-containing protein 55 isoform X2

    UniProtKB/TrEMBL
    A7MCU1, E9Q0E9
    Conserved Domains (2) summary
    PHA03095
    Location:3 → 286
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:64 → 95
    ANK; ANK repeat [structural motif]

  5. XM_006517791.5 → XP_006517854.1  ankyrin repeat domain-containing protein 55 isoform X2

    See identical proteins and their annotated locations for XP_006517854.1

    UniProtKB/TrEMBL
    A7MCU1, E9Q0E9
    Conserved Domains (2) summary
    PHA03095
    Location:3 → 286
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:64 → 95
    ANK; ANK repeat [structural motif]

  6. XM_017315639.3 → XP_017171128.1  ankyrin repeat domain-containing protein 55 isoform X2

    UniProtKB/TrEMBL
    A7MCU1, E9Q0E9
    Conserved Domains (2) summary
    PHA03095
    Location:3 → 286
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:64 → 95
    ANK; ANK repeat [structural motif]

  7. XM_036158224.1 → XP_036014117.1  ankyrin repeat domain-containing protein 55 isoform X5

    Conserved Domains (2) summary
    sd00045
    Location:45 → 76
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:46 → 98
    Ank_4; Ankyrin repeats (many copies)

  8. XM_006517792.4 → XP_006517855.1  ankyrin repeat domain-containing protein 55 isoform X4

    Conserved Domains (2) summary
    sd00045
    Location:75 → 106
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:76 → 128
    Ank_4; Ankyrin repeats (many copies)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BLD6.2 GenPept UniProtKB/Swiss-Prot:Q8BLD6

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