Format

Send to:

Choose Destination

ANKRD55 ankyrin repeat domain 55 [ Homo sapiens (human) ]

Gene ID: 79722, updated on 12-Oct-2019

Summary

Official Symbol
ANKRD55provided by HGNC
Official Full Name
ankyrin repeat domain 55provided by HGNC
Primary source
HGNC:HGNC:25681
See related
Ensembl:ENSG00000164512 MIM:615189
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 1.8), lymph node (RPKM 0.8) and 10 other tissues See more
Orthologs

Genomic context

See ANKRD55 in Genome Data Viewer
Location:
5q11.2
Exon count:
14
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (56099680..56233330, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (55395507..55529186, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene interleukin 6 signal transducer Neighboring gene Sharpr-MPRA regulatory region 5314 Neighboring gene uncharacterized LOC441072 Neighboring gene uncharacterized LOC105378976 Neighboring gene uncharacterized LOC101928419 Neighboring gene RNA, U6 small nuclear 299, pseudogene Neighboring gene ribosomal protein L17 pseudogene 22 Neighboring gene RNA, 5S ribosomal pseudogene 184 Neighboring gene C1GALT1 pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 185 Neighboring gene proteasome 26S subunit, ATPase 1 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Biological, clinical and population relevance of 95 loci for blood lipids.
NHGRI GWA Catalog
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
NHGRI GWA Catalog
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
NHGRI GWA Catalog
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
NHGRI GWA Catalog
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
NHGRI GWA Catalog
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
NHGRI GWA Catalog
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
NHGRI GWA Catalog
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11795, MGC126013, MGC126014

General protein information

Preferred Names
ankyrin repeat domain-containing protein 55

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024669.3NP_078945.2  ankyrin repeat domain-containing protein 55

    See identical proteins and their annotated locations for NP_078945.2

    Status: VALIDATED

    Source sequence(s)
    AK123389, AW269928, DA292581
    Consensus CDS
    CCDS34161.1
    UniProtKB/Swiss-Prot
    Q3KP44
    Related
    ENSP00000342295.4, ENST00000341048.9
    Conserved Domains (3) summary
    cd00204
    Location:121250
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:199295
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6091
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    56099680..56233330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009852.1XP_016865341.1  ankyrin repeat domain-containing protein 55 isoform X1

  2. XM_017009853.1XP_016865342.1  ankyrin repeat domain-containing protein 55 isoform X2

    UniProtKB/Swiss-Prot
    Q3KP44
    Related
    ENSP00000424230.1, ENST00000504958.6
    Conserved Domains (3) summary
    cd00204
    Location:121250
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:199295
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6091
    ANK; ANK repeat [structural motif]
  3. XM_017009854.1XP_016865343.1  ankyrin repeat domain-containing protein 55 isoform X3

  4. XM_011543646.1XP_011541948.1  ankyrin repeat domain-containing protein 55 isoform X4

    Related
    ENSP00000429421.1, ENST00000434982.2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001039935.1: Suppressed sequence

    Description
    NM_001039935.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Support Center