U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ANKRD55 ankyrin repeat domain 55 [ Homo sapiens (human) ]

Gene ID: 79722, updated on 22-May-2022

Summary

Official Symbol
ANKRD55provided by HGNC
Official Full Name
ankyrin repeat domain 55provided by HGNC
Primary source
HGNC:HGNC:25681
See related
Ensembl:ENSG00000164512 MIM:615189; AllianceGenome:HGNC:25681
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 1.8), lymph node (RPKM 0.8) and 10 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ANKRD55 in Genome Data Viewer
Location:
5q11.2
Exon count:
13
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (56099680..56233330, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (56928078..57060891, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (55395507..55529157, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 5314 Neighboring gene IL6ST divergent transcript Neighboring gene uncharacterized LOC105378976 Neighboring gene Sharpr-MPRA regulatory region 6268 Neighboring gene uncharacterized LOC101928419 Neighboring gene RNA, U6 small nuclear 299, pseudogene Neighboring gene ribosomal protein L17 pseudogene 22 Neighboring gene RNA, 5S ribosomal pseudogene 184 Neighboring gene Sharpr-MPRA regulatory region 5241 Neighboring gene C1GALT1 pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 185 Neighboring gene proteasome 26S subunit, ATPase 1 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Biological, clinical and population relevance of 95 loci for blood lipids.
EBI GWAS Catalog
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
EBI GWAS Catalog
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
EBI GWAS Catalog
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
EBI GWAS Catalog
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
EBI GWAS Catalog
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
EBI GWAS Catalog
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
EBI GWAS Catalog
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11795, MGC126013, MGC126014

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
ankyrin repeat domain-containing protein 55

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024669.3NP_078945.2  ankyrin repeat domain-containing protein 55

    See identical proteins and their annotated locations for NP_078945.2

    Status: VALIDATED

    Source sequence(s)
    AK123389, AW269928, DA292581
    Consensus CDS
    CCDS34161.1
    UniProtKB/Swiss-Prot
    Q3KP44
    Related
    ENSP00000342295.4, ENST00000341048.9
    Conserved Domains (3) summary
    cd00204
    Location:121250
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:199295
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:6091
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    56099680..56233330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047417710.1XP_047273666.1  ankyrin repeat domain-containing protein 55 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    56928078..57060891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001039935.1: Suppressed sequence

    Description
    NM_001039935.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.