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Cluap1 clusterin associated protein 1 [ Mus musculus (house mouse) ]

Gene ID: 76779, updated on 9-May-2024

Summary

Official Symbol
Cluap1provided by MGI
Official Full Name
clusterin associated protein 1provided by MGI
Primary source
MGI:MGI:1924029
See related
Ensembl:ENSMUSG00000014232 AllianceGenome:MGI:1924029
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310030D15Rik; 2610111M03Rik
Summary
Acts upstream of or within several processes, including axoneme assembly; embryonic morphogenesis; and left/right pattern formation. Located in centrosome; ciliary base; and ciliary tip. Part of intraciliary transport particle A and intraciliary transport particle B. Is expressed in several structures, including cranial ganglion; neural tube; olfactory epithelium; respiratory system; and thymus primordium. Orthologous to human CLUAP1 (clusterin associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 9.6), CNS E18 (RPKM 6.3) and 26 other tissues See more
Orthologs
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Genomic context

See Cluap1 in Genome Data Viewer
Location:
16 A1; 16 2.3 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (3725058..3760163)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (3907194..3942299)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5522 Neighboring gene olfactory receptor family 2 subfamily C member 1 Neighboring gene zinc finger protein 174 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:3872304-3872526 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:3872697-3872880 Neighboring gene zinc finger protein 597 Neighboring gene STARR-positive B cell enhancer mm9_chr16:3884448-3884748 Neighboring gene N(alpha)-acetyltransferase 60, NatF catalytic subunit Neighboring gene RIKEN cDNA 1700037C18 gene Neighboring gene predicted gene, 41410 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:3908535-3908837 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:3909019-3909128 Neighboring gene prothymosin alpha-like Neighboring gene predicted gene 15539 Neighboring gene predicted gene, 57636 Neighboring gene NLR family, CARD domain containing 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:3976439-3976665 Neighboring gene SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in ciliary base IDA
Inferred from Direct Assay
more info
PubMed 
located_in ciliary tip IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cilium IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cilium NAS
Non-traceable Author Statement
more info
PubMed 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
part_of intraciliary transport particle A IDA
Inferred from Direct Assay
more info
PubMed 
part_of intraciliary transport particle B IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of intraciliary transport particle B IDA
Inferred from Direct Assay
more info
PubMed 
part_of intraciliary transport particle B ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
clusterin-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419018.1NP_001405947.1  clusterin-associated protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC129021
  2. NM_001419019.1NP_001405948.1  clusterin-associated protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC129021
  3. NM_001419020.1NP_001405949.1  clusterin-associated protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC129021
  4. NM_001419021.1NP_001405950.1  clusterin-associated protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC129021
  5. NM_001419022.1NP_001405951.1  clusterin-associated protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC129021
  6. NM_001419023.1NP_001405952.1  clusterin-associated protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC129021
  7. NM_001419024.1NP_001405953.1  clusterin-associated protein 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC129021
  8. NM_001419025.1NP_001405954.1  clusterin-associated protein 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC129021
  9. NM_001419026.1NP_001405955.1  clusterin-associated protein 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC129021
  10. NM_001419027.1NP_001405956.1  clusterin-associated protein 1 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC129021
  11. NM_001419028.1NP_001405957.1  clusterin-associated protein 1 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC129021
  12. NM_029738.3NP_084014.1  clusterin-associated protein 1 isoform 1

    See identical proteins and their annotated locations for NP_084014.1

    Status: VALIDATED

    Source sequence(s)
    AC129021
    Consensus CDS
    CCDS27912.1
    UniProtKB/Swiss-Prot
    Q6P3Y8, Q8R3P7
    Related
    ENSMUSP00000043397.8, ENSMUST00000040881.14
    Conserved Domains (2) summary
    pfam10234
    Location:19278
    Cluap1; Clusterin-associated protein-1
    cl23887
    Location:182308
    DUF4349; Domain of unknown function (DUF4349)

RNA

  1. NR_185001.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC129021
  2. NR_185002.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC129021

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    3725058..3760163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317157.2XP_017172646.2  clusterin-associated protein 1 isoform X1

    Conserved Domains (1) summary
    pfam10234
    Location:111370
    Cluap1; Clusterin-associated protein-1
  2. XM_006522701.5XP_006522764.5  clusterin-associated protein 1 isoform X2

    Conserved Domains (1) summary
    pfam10234
    Location:57326
    Cluap1; Clusterin-associated protein-1
  3. XM_006522702.4XP_006522765.1  clusterin-associated protein 1 isoform X3

    Conserved Domains (1) summary
    pfam10234
    Location:20279
    Cluap1; Clusterin-associated protein-1
  4. XM_006522704.5XP_006522767.1  clusterin-associated protein 1 isoform X5

    See identical proteins and their annotated locations for XP_006522767.1

    Conserved Domains (1) summary
    pfam10234
    Location:8267
    Cluap1; Clusterin-associated protein-1
  5. XM_006522705.5XP_006522768.1  clusterin-associated protein 1 isoform X5

    See identical proteins and their annotated locations for XP_006522768.1

    Conserved Domains (1) summary
    pfam10234
    Location:8267
    Cluap1; Clusterin-associated protein-1
  6. XM_030249328.2XP_030105188.1  clusterin-associated protein 1 isoform X7

    Conserved Domains (1) summary
    pfam10234
    Location:3272
    Cluap1; Clusterin-associated protein-1
  7. XM_006522706.4XP_006522769.1  clusterin-associated protein 1 isoform X8

    Conserved Domains (1) summary
    pfam10234
    Location:194
    Cluap1; Clusterin-associated protein-1