U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bicdl1 BICD family like cargo adaptor 1 [ Mus musculus (house mouse) ]

Gene ID: 75665, updated on 8-Nov-2022

Summary

Official Symbol
Bicdl1provided by MGI
Official Full Name
BICD family like cargo adaptor 1provided by MGI
Primary source
MGI:MGI:1922915
See related
Ensembl:ENSMUSG00000041609 AllianceGenome:MGI:1922915
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ccdc64; BICDR-1; 2210403N09Rik
Summary
Enables dynactin binding activity and small GTPase binding activity. Involved in Golgi to secretory granule transport and neuron projection development. Located in centrosome. Is expressed in several structures, including adrenal gland; genitourinary system; gut; nervous system; and sensory organ. Orthologous to human BICDL1 (BICD family like cargo adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 26.8), CNS E18 (RPKM 20.2) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Bicdl1 in Genome Data Viewer
Location:
5; 5 F
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115786233..115869824, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115648174..115731844, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1110006O24 gene Neighboring gene RAB35, member RAS oncogene family Neighboring gene microRNA 7030 Neighboring gene ribosomal protein L29 Neighboring gene citron Neighboring gene predicted gene, 42008

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC143541

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dynactin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi to secretory granule transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in Golgi to secretory granule transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
involved_in neuron projection development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle transport along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BICD family-like cargo adapter 1
Names
BICD-related protein 1
bicaudal D-related protein 1
coiled-coil domain containing 64
coiled-coil domain-containing protein 64A

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080808.2NP_001074277.1  BICD family-like cargo adapter 1

    See identical proteins and their annotated locations for NP_001074277.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AC139562, GU973876
    Consensus CDS
    CCDS39230.1
    UniProtKB/Swiss-Prot
    A0JNT9, Q8R1D2
    Related
    ENSMUSP00000053547.7, ENSMUST00000055408.13
    Conserved Domains (1) summary
    TIGR02168
    Location:101331
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RNA

  1. NR_151598.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains three alternate exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC139562, AC159539
  2. NR_151599.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains three alternate exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC139562, AC159539
  3. NR_151600.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' end and contains and alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC159539
  4. NR_151601.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' end and contains and alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC159539
  5. NR_151602.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC159539
  6. NR_151603.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC159539

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    115786233..115869824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530487.4XP_006530550.1  BICD family-like cargo adapter 1 isoform X2

    Conserved Domains (1) summary
    TIGR02168
    Location:101331
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_006530489.4XP_006530552.1  BICD family-like cargo adapter 1 isoform X3

    Conserved Domains (1) summary
    TIGR02168
    Location:101335
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  3. XM_006530490.5XP_006530553.1  BICD family-like cargo adapter 1 isoform X1

    Conserved Domains (1) summary
    TIGR02168
    Location:101335
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RNA

  1. XR_003955719.2 RNA Sequence