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Cmtm2b CKLF-like MARVEL transmembrane domain containing 2B [ Mus musculus (house mouse) ]

Gene ID: 75502, updated on 11-Apr-2024

Summary

Official Symbol
Cmtm2bprovided by MGI
Official Full Name
CKLF-like MARVEL transmembrane domain containing 2Bprovided by MGI
Primary source
MGI:MGI:2447311
See related
Ensembl:ENSMUSG00000035785 AllianceGenome:MGI:2447311
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cklfsf22; Cklfsf2b; 1700013O04Rik
Summary
Predicted to enable cytokine activity. Predicted to act upstream of or within chemotaxis. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Orthologous to human CMTM2 (CKLF like MARVEL transmembrane domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 279.9) See more
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Genomic context

See Cmtm2b in Genome Data Viewer
Location:
8 D3; 8 53.04 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (105048838..105057396)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (104322206..104330764)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CKLF-like MARVEL transmembrane domain containing 1 Neighboring gene predicted gene 45710 Neighboring gene CKLF-like MARVEL transmembrane domain containing 3 Neighboring gene CKLF-like MARVEL transmembrane domain containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chemotaxis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
CKLF-like MARVEL transmembrane domain-containing protein 2B
Names
chemokine-like factor super family 2B
chemokine-like factor superfamily member 2B
chemokine-like factor superfamily protein 2-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028524.3NP_082800.1  CKLF-like MARVEL transmembrane domain-containing protein 2B

    See identical proteins and their annotated locations for NP_082800.1

    Status: VALIDATED

    Source sequence(s)
    AC121952, AK005970, BC050983
    Consensus CDS
    CCDS22576.1
    UniProtKB/Swiss-Prot
    Q9DAC0
    Related
    ENSMUSP00000043127.6, ENSMUST00000041973.7
    Conserved Domains (1) summary
    pfam01284
    Location:35120
    MARVEL; Membrane-associating domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    105048838..105057396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531455.4XP_006531518.1  CKLF-like MARVEL transmembrane domain-containing protein 2B isoform X1

    Conserved Domains (1) summary
    cl04571
    Location:35120
    MARVEL; Membrane-associating domain