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Nop14 NOP14 nucleolar protein [ Mus musculus (house mouse) ]

Gene ID: 75416, updated on 11-Apr-2024

Summary

Official Symbol
Nop14provided by MGI
Official Full Name
NOP14 nucleolar proteinprovided by MGI
Primary source
MGI:MGI:1922666
See related
Ensembl:ENSMUSG00000036693 AllianceGenome:MGI:1922666
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nol14; 2610033H07Rik
Summary
Predicted to enable enzyme binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in alimentary system; central nervous system; ganglia; lower urinary tract; and sensory organ. Orthologous to human NOP14 (NOP14 nucleolar protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 21.6), CNS E11.5 (RPKM 11.5) and 28 other tissues See more
Orthologs
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Genomic context

See Nop14 in Genome Data Viewer
Location:
5 B2; 5 17.91 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (34795880..34817566, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (34638536..34660148, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12845 Neighboring gene microRNA 7036b Neighboring gene adducin 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34979450-34979637 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:35002815-35002998 Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene predicted gene 15522 Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene microRNA 467g Neighboring gene STARR-positive B cell enhancer ABC_E1050 Neighboring gene huntingtin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Noc4p-Nop14p complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
nucleolar protein 14
Names
NOP14 nucleolar protein homolog
nucleolar complex protein 14
probable nucleolar complex protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029278.3NP_083554.2  nucleolar protein 14

    See identical proteins and their annotated locations for NP_083554.2

    Status: VALIDATED

    Source sequence(s)
    AC115695, AC151669
    Consensus CDS
    CCDS19218.1
    UniProtKB/Swiss-Prot
    Q5RL78, Q8R3N1
    UniProtKB/TrEMBL
    Q3TSX5
    Related
    ENSMUSP00000038382.10, ENSMUST00000041364.13
    Conserved Domains (1) summary
    pfam04147
    Location:24849
    Nop14; Nop14-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    34795880..34817566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_376833.5 RNA Sequence