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Cep128 centrosomal protein 128 [ Mus musculus (house mouse) ]

Gene ID: 75216, updated on 5-Mar-2024

Summary

Official Symbol
Cep128provided by MGI
Official Full Name
centrosomal protein 128provided by MGI
Primary source
MGI:MGI:1922466
See related
Ensembl:ENSMUSG00000061533 AllianceGenome:MGI:1922466
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E230024F20; 4930534B04Rik; 5430424K18Rik
Summary
Predicted to be involved in protein localization. Predicted to be located in centriole and spindle pole. Predicted to be part of centriolar subdistal appendage. Orthologous to human CEP128 (centrosomal protein 128). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 30.8), liver E14 (RPKM 3.1) and 2 other tissues See more
Orthologs
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Genomic context

Location:
12 D3; 12 44.08 cM
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (90965264..91351207, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (90998490..91384455, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26512 Neighboring gene STARR-seq mESC enhancer starr_32925 Neighboring gene nuclear encoded rRNA 5S 65 Neighboring gene predicted gene, 23195 Neighboring gene STARR-seq mESC enhancer starr_32926 Neighboring gene STARR-seq mESC enhancer starr_32927 Neighboring gene RIKEN cDNA 5430427M07 gene Neighboring gene MOCO sulphurase C-terminal domain containing 2 pseudogene Neighboring gene phosphatidate cytidylyltransferase, mitochondrial pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr12:92497477-92497778 Neighboring gene STARR-seq mESC enhancer starr_32928 Neighboring gene STARR-seq mESC enhancer starr_32929 Neighboring gene predicted gene, 18388 Neighboring gene STARR-positive B cell enhancer ABC_E8495 Neighboring gene thyroid stimulating hormone receptor Neighboring gene phosphoglycerate mutase family member 5 pseudogene Neighboring gene predicted gene, 40541

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
part_of centriolar subdistal appendage ISO
Inferred from Sequence Orthology
more info
 
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriole IDA
Inferred from Direct Assay
more info
PubMed 
located_in centriole ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in sperm connecting piece ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
centrosomal protein of 128 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181815.3NP_861536.3  centrosomal protein of 128 kDa

    See identical proteins and their annotated locations for NP_861536.3

    Status: VALIDATED

    Source sequence(s)
    BC079647, CK634985
    Consensus CDS
    CCDS36515.2
    UniProtKB/Swiss-Prot
    Q8BI22
    UniProtKB/TrEMBL
    B7ZNX8
    Related
    ENSMUSP00000115679.2, ENSMUST00000141429.8
    Conserved Domains (1) summary
    pfam07851
    Location:612705
    TMPIT; TMPIT-like protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    90965264..91351207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244197.3XP_011242499.1  centrosomal protein of 128 kDa isoform X6

    See identical proteins and their annotated locations for XP_011242499.1

    Conserved Domains (2) summary
    COG1196
    Location:222602
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:48367
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_030246965.2XP_030102825.1  centrosomal protein of 128 kDa isoform X3

    Conserved Domains (4) summary
    COG1196
    Location:406786
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG4372
    Location:268491
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    TIGR02169
    Location:694925
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    TIGR03794
    Location:151323
    NHLM_micro_HlyD; NHLM bacteriocin system secretion protein
  3. XM_011244195.4XP_011242497.1  centrosomal protein of 128 kDa isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:406786
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:222544
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
  4. XM_006516324.5XP_006516387.1  centrosomal protein of 128 kDa isoform X1

    Conserved Domains (1) summary
    COG1196
    Location:451831
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  5. XM_017315228.3XP_017170717.1  centrosomal protein of 128 kDa isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:295675
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:23795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  6. XM_036157636.1XP_036013529.1  centrosomal protein of 128 kDa isoform X7

    Conserved Domains (2) summary
    COG1196
    Location:222602
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:48367
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  7. XM_030246966.2XP_030102826.1  centrosomal protein of 128 kDa isoform X6

    Conserved Domains (2) summary
    COG1196
    Location:222602
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:48367
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  8. XM_011244196.4XP_011242498.1  centrosomal protein of 128 kDa isoform X5

    Conserved Domains (3) summary
    COG1196
    Location:451831
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:281612
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    TIGR03794
    Location:151323
    NHLM_micro_HlyD; NHLM bacteriocin system secretion protein

RNA

  1. XR_001780497.3 RNA Sequence