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CEP128 centrosomal protein 128 [ Homo sapiens (human) ]

Gene ID: 145508, updated on 4-Jul-2021

Summary

Official Symbol
CEP128provided by HGNC
Official Full Name
centrosomal protein 128provided by HGNC
Primary source
HGNC:HGNC:20359
See related
Ensembl:ENSG00000100629
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf61; LEDP/132; C14orf145
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See CEP128 in Genome Data Viewer
Location:
14q31.1
Exon count:
32
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (80478321..80959501, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (80962822..81408082, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370593 Neighboring gene DIO2 antisense RNA 1 Neighboring gene iodothyronine deiodinase 2 Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 2 Neighboring gene basic helix-loop-helix family member b9 pseudogene 1 Neighboring gene thyroid stimulating hormone receptor Neighboring gene ribosomal protein L17 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of centriolar subdistal appendage IDA
Inferred from Direct Assay
more info
PubMed 
located_in centriole IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
centrosomal protein of 128 kDa
Names
centrosomal protein 128kDa
lens epithelium-derived protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152446.5NP_689659.2  centrosomal protein of 128 kDa

    See identical proteins and their annotated locations for NP_689659.2

    Status: VALIDATED

    Source sequence(s)
    AC010072, AC018513, AC022404, KF455965
    Consensus CDS
    CCDS32130.1
    UniProtKB/Swiss-Prot
    Q6ZU80
    UniProtKB/TrEMBL
    Q86TS1
    Related
    ENSP00000451162.1, ENST00000555265.6
    Conserved Domains (4) summary
    pfam01442
    Location:200373
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    pfam10212
    Location:290530
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:676776
    DUF342; Protein of unknown function (DUF342)
    cl19511
    Location:184295
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)

RNA

  1. NR_157142.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC010072, AC018513, AC022404, KF455965

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    80478321..80959501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011536491.2XP_011534793.1  centrosomal protein of 128 kDa isoform X1

    See identical proteins and their annotated locations for XP_011534793.1

    Conserved Domains (3) summary
    pfam05483
    Location:192828
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam10212
    Location:290530
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:676776
    DUF342; Protein of unknown function (DUF342)
  2. XM_011536493.2XP_011534795.1  centrosomal protein of 128 kDa isoform X3

    Conserved Domains (3) summary
    pfam05483
    Location:192828
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam10212
    Location:290530
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:676776
    DUF342; Protein of unknown function (DUF342)
  3. XM_011536492.2XP_011534794.1  centrosomal protein of 128 kDa isoform X1

    See identical proteins and their annotated locations for XP_011534794.1

    Conserved Domains (3) summary
    pfam05483
    Location:192828
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam10212
    Location:290530
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:676776
    DUF342; Protein of unknown function (DUF342)
  4. XM_011536490.2XP_011534792.1  centrosomal protein of 128 kDa isoform X1

    See identical proteins and their annotated locations for XP_011534792.1

    Conserved Domains (3) summary
    pfam05483
    Location:192828
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam10212
    Location:290530
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:676776
    DUF342; Protein of unknown function (DUF342)
  5. XM_017021042.1XP_016876531.1  centrosomal protein of 128 kDa isoform X4

    Conserved Domains (3) summary
    pfam01442
    Location:58231
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    pfam10212
    Location:148388
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:534634
    DUF342; Protein of unknown function (DUF342)
  6. XM_017021043.1XP_016876532.1  centrosomal protein of 128 kDa isoform X6

  7. XM_011536495.2XP_011534797.1  centrosomal protein of 128 kDa isoform X5

    Conserved Domains (3) summary
    pfam01442
    Location:200373
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    pfam10212
    Location:290530
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein
    cl19219
    Location:676776
    DUF342; Protein of unknown function (DUF342)
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