U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slc7a13 solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 [ Mus musculus (house mouse) ]

Gene ID: 74087, updated on 8-Feb-2024

Summary

Official Symbol
Slc7a13provided by MGI
Official Full Name
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13provided by MGI
Primary source
MGI:MGI:1921337
See related
Ensembl:ENSMUSG00000041052 AllianceGenome:MGI:1921337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AGT1; XAT2; AGT-1; 0610009O04Rik
Summary
Enables protein heterodimerization activity. Involved in L-cystine transport; L-glutamate transmembrane transport; and aspartate transmembrane transport. Is active in apical plasma membrane. Is expressed in ileum; liver; male reproductive gland or organ; and metanephros. Orthologous to human SLC7A13 (solute carrier family 7 member 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Slc7a13 in Genome Data Viewer
Location:
4 A3; 4 7.63 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (19818727..19842213)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (19818727..19842213)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene WW domain containing E3 ubiquitin protein ligase 1 Neighboring gene predicted gene 12353 Neighboring gene STARR-positive B cell enhancer ABC_E9583 Neighboring gene STARR-positive B cell enhancer ABC_E2687 Neighboring gene predicted gene 12354 Neighboring gene STARR-seq mESC enhancer starr_09699 Neighboring gene STARR-seq mESC enhancer starr_09700 Neighboring gene STARR-seq mESC enhancer starr_09702 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit D2 Neighboring gene STARR-seq mESC enhancer starr_09703 Neighboring gene RIKEN cDNA 4930480G23 gene Neighboring gene STARR-seq mESC enhancer starr_09704

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in L-cystine transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in L-glutamate transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within amino acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in aspartate transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane IC
Inferred by Curator
more info
PubMed 
is_active_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in apical plasma membrane IPI
Inferred from Physical Interaction
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 7 member 13
Names
X-amino acid transporter 2
aspartate/glutamate transporter 1
sodium-independent aspartate/glutamate transporter 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028746.3NP_083022.1  solute carrier family 7 member 13

    See identical proteins and their annotated locations for NP_083022.1

    Status: VALIDATED

    Source sequence(s)
    AK143768, CK346971
    Consensus CDS
    CCDS17993.1
    UniProtKB/Swiss-Prot
    Q91WN3
    Related
    ENSMUSP00000036228.8, ENSMUST00000035890.8
    Conserved Domains (1) summary
    TIGR00911
    Location:2466
    2A0308; L-type amino acid transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    19818727..19842213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)