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Ift70b intraflagellar transport 70B [ Mus musculus (house mouse) ]

Gene ID: 72421, updated on 30-Apr-2024

Summary

Official Symbol
Ift70bprovided by MGI
Official Full Name
intraflagellar transport 70Bprovided by MGI
Primary source
MGI:MGI:1919671
See related
Ensembl:ENSMUSG00000075273 AllianceGenome:MGI:1919671
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tcc30b; Ttc30b; 2510042P03Rik
Summary
Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to act upstream of or within cell projection organization. Part of intraciliary transport particle B. Orthologous to several human genes including TTC30B (tetratricopeptide repeat domain 30B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
2 C3; 2 44.79 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (75766193..75768806, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (75935849..75938462, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 13669 Neighboring gene STARR-positive B cell enhancer mm9_chr2:75661802-75662103 Neighboring gene predicted gene, 34861 Neighboring gene STARR-positive B cell enhancer ABC_E10117 Neighboring gene alkylglycerone phosphate synthase Neighboring gene STARR-seq mESC enhancer starr_04879 Neighboring gene predicted gene, 54164 Neighboring gene intraflagellar transport 70A2

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables intraciliary transport particle B binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly NAS
Non-traceable Author Statement
more info
PubMed 
involved_in intraciliary anterograde transport NAS
Non-traceable Author Statement
more info
PubMed 
involved_in intraciliary transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within intraciliary transport IC
Inferred by Curator
more info
PubMed 
Component Evidence Code Pubs
is_active_in axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cilium IC
Inferred by Curator
more info
PubMed 
located_in cilium NAS
Non-traceable Author Statement
more info
PubMed 
part_of intraciliary transport particle B IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of intraciliary transport particle B IDA
Inferred from Direct Assay
more info
PubMed 
part_of intraciliary transport particle B ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
intraflagellar transport protein 70B
Names
TPR repeat protein 30B
novel tetratrico peptide repeat (TPR) containing protein
tetratricopeptide repeat domain 30B
tetratricopeptide repeat protein 30B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028235.1NP_082511.1  intraflagellar transport protein 70B

    See identical proteins and their annotated locations for NP_082511.1

    Status: VALIDATED

    Source sequence(s)
    AL773533, BC026507
    Consensus CDS
    CCDS38150.1
    UniProtKB/Swiss-Prot
    Q3UI02, Q9CY00
    UniProtKB/TrEMBL
    B2RXA2
    Related
    ENSMUSP00000097576.4, ENSMUST00000099996.5
    Conserved Domains (2) summary
    TIGR02917
    Location:15216
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:157181
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    75766193..75768806 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)