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IFT70B intraflagellar transport 70B [ Homo sapiens (human) ]

Gene ID: 150737, updated on 2-Nov-2024

Summary

Official Symbol
IFT70Bprovided by HGNC
Official Full Name
intraflagellar transport 70Bprovided by HGNC
Primary source
HGNC:HGNC:26425
See related
Ensembl:ENSG00000196659 MIM:620742; AllianceGenome:HGNC:26425
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IFT70; fleer; TTC30B
Summary
Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Part of intraciliary transport particle B. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See IFT70B in Genome Data Viewer
Location:
2q31.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (177548998..177552796, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (178031273..178035071, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (178413726..178417524, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene Putative uncharacterized protein FLJ44553 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12146 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12147 Neighboring gene Sharpr-MPRA regulatory region 2066 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:178261250-178261750 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:178275762-178275927 Neighboring gene alkylglycerone phosphate synthase Neighboring gene MPRA-validated peak3947 silencer Neighboring gene uncharacterized LOC105373762 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:178338764-178339963 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:178416524-178417328 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:178417329-178418132 Neighboring gene uncharacterized LOC124906098 Neighboring gene intraflagellar transport 70A

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ30990

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables intraciliary transport particle B binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cilium assembly NAS
Non-traceable Author Statement
more info
PubMed 
involved_in intraciliary anterograde transport NAS
Non-traceable Author Statement
more info
PubMed 
involved_in intraciliary transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ciliary tip TAS
Traceable Author Statement
more info
 
located_in cilium NAS
Non-traceable Author Statement
more info
PubMed 
located_in cilium TAS
Traceable Author Statement
more info
 
part_of intraciliary transport particle B IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of intraciliary transport particle B IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
intraflagellar transport protein 70B
Names
TPR repeat protein 30B
tetratricopeptide repeat domain 30B
tetratricopeptide repeat protein 30B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152517.3NP_689730.2  intraflagellar transport protein 70B

    See identical proteins and their annotated locations for NP_689730.2

    Status: VALIDATED

    Source sequence(s)
    AC073834, AI498353, AW007843, BC033795, DA260391, DA557876
    Consensus CDS
    CCDS42784.1
    UniProtKB/Swiss-Prot
    Q63HQ1, Q8N4P2, Q96NE6
    UniProtKB/TrEMBL
    B4DL36
    Related
    ENSP00000386181.2, ENST00000408939.4
    Conserved Domains (2) summary
    TIGR02917
    Location:26217
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:158182
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    177548998..177552796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    178031273..178035071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)