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TTC30B tetratricopeptide repeat domain 30B [ Homo sapiens (human) ]

Gene ID: 150737, updated on 6-Sep-2022

Summary

Official Symbol
TTC30Bprovided by HGNC
Official Full Name
tetratricopeptide repeat domain 30Bprovided by HGNC
Primary source
HGNC:HGNC:26425
See related
Ensembl:ENSG00000196659 AllianceGenome:HGNC:26425
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IFT70; fleer; IFT70B
Summary
Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to be located in ciliary tip. Predicted to be part of intraciliary transport particle B. Predicted to be active in axonemal microtubule and ciliary basal body. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See TTC30B in Genome Data Viewer
Location:
2q31.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (177548998..177552796, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (178031273..178035071, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (178413726..178417524, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 14377 Neighboring gene alkylglycerone phosphate synthase Neighboring gene uncharacterized LOC105373762 Neighboring gene uncharacterized LOC124906098 Neighboring gene tetratricopeptide repeat domain 30A

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ30990

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables intraciliary transport particle B binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IC
Inferred by Curator
more info
PubMed 
involved_in intraciliary anterograde transport IC
Inferred by Curator
more info
PubMed 
involved_in intraciliary transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in ciliary tip TAS
Traceable Author Statement
more info
 
located_in cilium IC
Inferred by Curator
more info
PubMed 
located_in cilium TAS
Traceable Author Statement
more info
 
part_of intraciliary transport particle B IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of intraciliary transport particle B IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
tetratricopeptide repeat protein 30B
Names
TPR repeat protein 30B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152517.3NP_689730.2  tetratricopeptide repeat protein 30B

    See identical proteins and their annotated locations for NP_689730.2

    Status: VALIDATED

    Source sequence(s)
    AC073834, AI498353, AW007843, BC033795, DA260391, DA557876
    Consensus CDS
    CCDS42784.1
    UniProtKB/Swiss-Prot
    Q8N4P2, Q96NE6
    Related
    ENSP00000386181.2, ENST00000408939.4
    Conserved Domains (2) summary
    TIGR02917
    Location:26217
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:158182
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    177548998..177552796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    178031273..178035071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)