Wdr89 WD repeat domain 89 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Wdr89provided by MGI
Official Full Name: WD repeat domain 89provided by MGI
Primary source: MGI:MGI:1919588
See related: Ensembl:ENSMUSG00000045690 AllianceGenome:MGI:1919588
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2600001A11Rik
Summary: Orthologous to human WDR89 (WD repeat domain 89). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 32.8), liver E14 (RPKM 30.2) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12; 12 C3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (75677368..75716311, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (75630594..75669537, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)
Chemically induced (ENU) (1)

General gene information

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Markers

RH136584 (e-PCR)
- UniSTS:210564

NoName (e-PCR)
- UniSTS:488868

Homology

Homologs of the Wdr89 gene: The Wdr89 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
Orthologs from Annotation Pipeline: 483 organisms have orthologs with human gene Wdr89
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within corpus callosum development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within ventricular system development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: WD repeat-containing protein 89

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_028203.1 → NP_082479.1 WD repeat-containing protein 89

See identical proteins and their annotated locations for NP_082479.1

Status: VALIDATED

Source sequence(s)

AC124742

Consensus CDS

CCDS49090.1

UniProtKB/Swiss-Prot

Q9D0R9

Related

ENSMUSP00000050532.8, ENSMUST00000062370.9

Conserved Domains (3) summary

COG2319
Location:65 → 348

WD40; WD40 repeat [General function prediction only]

sd00039
Location:74 → 111

7WD40; WD40 repeat [structural motif]

cl02567
Location:38 → 348

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...