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WDR89 WD repeat domain 89 [ Homo sapiens (human) ]

Gene ID: 112840, updated on 7-May-2020

Summary

Official Symbol
WDR89provided by HGNC
Official Full Name
WD repeat domain 89provided by HGNC
Primary source
HGNC:HGNC:20489
See related
Ensembl:ENSG00000140006
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MSTP050; C14orf150
Expression
Ubiquitous expression in lymph node (RPKM 4.5), thyroid (RPKM 4.4) and 25 other tissues See more
Orthologs

Genomic context

See WDR89 in Genome Data Viewer
Location:
14q23.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (63597039..63641871, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (64063757..64108641, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31 pseudogene 5 Neighboring gene glycine C-acetyltransferase pseudogene 1 Neighboring gene heat shock protein family E (Hsp10) member 1 pseudogene 2 Neighboring gene RNA, U6 small nuclear 597, pseudogene Neighboring gene RNA, U6 small nuclear 1162, pseudogene Neighboring gene uncharacterized LOC105370532 Neighboring gene sphingosine-1-phosphate phosphatase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC9907

Gene Ontology Provided by GOA

Process Evidence Code Pubs
corpus callosum development IEA
Inferred from Electronic Annotation
more info
 
ventricular system development IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
WD repeat-containing protein 89

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008726.3NP_001008726.1  WD repeat-containing protein 89

    See identical proteins and their annotated locations for NP_001008726.1

    Status: VALIDATED

    Source sequence(s)
    BC010698, BP278550, DA882425
    Consensus CDS
    CCDS9759.1
    UniProtKB/Swiss-Prot
    Q96FK6
    UniProtKB/TrEMBL
    A0A024R667
    Conserved Domains (3) summary
    COG2319
    Location:31349
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:74112
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:41349
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_001258272.2NP_001245201.1  WD repeat-containing protein 89

    See identical proteins and their annotated locations for NP_001245201.1

    Status: VALIDATED

    Source sequence(s)
    BC010698, BP278550, DA882425, DB178690
    Consensus CDS
    CCDS9759.1
    UniProtKB/Swiss-Prot
    Q96FK6
    UniProtKB/TrEMBL
    A0A024R667
    Related
    ENSP00000267522.3, ENST00000267522.7
    Conserved Domains (3) summary
    COG2319
    Location:31349
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:74112
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:41349
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. NM_001382423.1NP_001369352.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  4. NM_001382424.1NP_001369353.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  5. NM_001382425.1NP_001369354.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  6. NM_001382426.1NP_001369355.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  7. NM_001382427.1NP_001369356.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  8. NM_001382428.1NP_001369357.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  9. NM_001382429.1NP_001369358.1  WD repeat-containing protein 89

    Status: VALIDATED

    Source sequence(s)
    AL136038
  10. NM_080666.4NP_542397.1  WD repeat-containing protein 89

    See identical proteins and their annotated locations for NP_542397.1

    Status: VALIDATED

    Source sequence(s)
    BC010698, DA882425
    Consensus CDS
    CCDS9759.1
    UniProtKB/Swiss-Prot
    Q96FK6
    UniProtKB/TrEMBL
    A0A024R667
    Related
    ENSP00000378399.2, ENST00000394942.2
    Conserved Domains (3) summary
    COG2319
    Location:31349
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:74112
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:41349
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    63597039..63641871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011536385.3XP_011534687.1  WD repeat-containing protein 89 isoform X2

    UniProtKB/Swiss-Prot
    Q96FK6
    UniProtKB/TrEMBL
    A0A024R667
    Related
    ENSP00000480112.1, ENST00000620954.1
    Conserved Domains (3) summary
    COG2319
    Location:31349
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:74112
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:41349
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_011536383.2XP_011534685.1  WD repeat-containing protein 89 isoform X1

    Conserved Domains (3) summary
    COG2319
    Location:69387
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:112150
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:79387
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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