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Trim29 tripartite motif-containing 29 [ Mus musculus (house mouse) ]

Gene ID: 72169, updated on 12-May-2024

Summary

Official Symbol
Trim29provided by MGI
Official Full Name
tripartite motif-containing 29provided by MGI
Primary source
MGI:MGI:1919419
See related
Ensembl:ENSMUSG00000032013 AllianceGenome:MGI:1919419
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110047J21Rik; 2810431N19Rik; 4732461M22Rik
Summary
Enables p53 binding activity. Acts upstream of or within negative regulation of protein localization to nucleus and negative regulation of transcription by RNA polymerase II. Located in cytoplasm. Is expressed in alimentary system; sensory organ; skin; and urethra. Orthologous to human TRIM29 (tripartite motif containing 29). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 26.2), bladder adult (RPKM 22.9) and 5 other tissues See more
Orthologs
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Genomic context

See Trim29 in Genome Data Viewer
Location:
9 A5.1; 9 24.28 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (43222012..43247422)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (43310715..43336125)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:43050540-43050727 Neighboring gene out at first homolog Neighboring gene VISTA enhancer mm1617 Neighboring gene RIKEN cDNA D630033O11 gene Neighboring gene STARR-seq mESC enhancer starr_23931 Neighboring gene predicted gene, 36799 Neighboring gene predicted gene, 47475

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables p53 binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tripartite motif-containing protein 29
Names
tripartite motif protein 29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023655.2NP_076144.2  tripartite motif-containing protein 29

    See identical proteins and their annotated locations for NP_076144.2

    Status: VALIDATED

    Source sequence(s)
    AC167973, AK013219, AK028448, BB612224
    Consensus CDS
    CCDS52775.1
    UniProtKB/Swiss-Prot
    Q8CEE2, Q8R2Q0, Q922Y3, Q99PN5, Q9CSC9
    Related
    ENSMUSP00000034511.6, ENSMUST00000034511.7
    Conserved Domains (2) summary
    pfam00643
    Location:221260
    zf-B_box; B-box zinc finger
    pfam03993
    Location:310372
    DUF349; Domain of Unknown Function (DUF349)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    43222012..43247422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510616.5XP_006510679.1  tripartite motif-containing protein 29 isoform X1

    See identical proteins and their annotated locations for XP_006510679.1

    Conserved Domains (3) summary
    pfam01442
    Location:275372
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    cd19769
    Location:223260
    Bbox2_TRIM16-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM16, TRIM29, TRIM47 and similar proteins
    cd19840
    Location:171217
    Bbox1_TRIM29; B-box-type 1 zinc finger found in tripartite motif-containing protein 29 (TRIM29) and similar proteins
  2. XM_006510617.5XP_006510680.1  tripartite motif-containing protein 29 isoform X2

    Conserved Domains (3) summary
    pfam01442
    Location:275372
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    cd19769
    Location:223260
    Bbox2_TRIM16-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM16, TRIM29, TRIM47 and similar proteins
    cd19840
    Location:171217
    Bbox1_TRIM29; B-box-type 1 zinc finger found in tripartite motif-containing protein 29 (TRIM29) and similar proteins