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Jmjd8 jumonji domain containing 8 [ Mus musculus (house mouse) ]

Gene ID: 72106, updated on 18-Apr-2024

Summary

Official Symbol
Jmjd8provided by MGI
Official Full Name
jumonji domain containing 8provided by MGI
Primary source
MGI:MGI:1919356
See related
Ensembl:ENSMUSG00000025736 AllianceGenome:MGI:1919356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610003J06Rik
Summary
Predicted to be involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of sprouting angiogenesis; and regulation of glycolytic process. Predicted to be located in endoplasmic reticulum lumen and nucleus. Predicted to be active in cytoplasm. Is expressed in brain; gonad; lung; metanephros; and submandibular gland. Orthologous to human JMJD8 (jumonji domain containing 8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 71.8), kidney adult (RPKM 66.5) and 28 other tissues See more
Orthologs
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Genomic context

Location:
17 A3.3; 17 12.92 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26048017..26050817)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25829043..25831843)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene F-box and leucine-rich repeat protein 16 Neighboring gene STARR-positive B cell enhancer ABC_E7500 Neighboring gene WD repeat domain 24 Neighboring gene STARR-positive B cell enhancer ABC_E3192 Neighboring gene microRNA 3082 Neighboring gene STIP1 homology and U-Box containing protein 1 Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1)  1 citation
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum lumen ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
jmjC domain-containing protein 8
Names
jumonji domain-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028101.5NP_082377.3  jmjC domain-containing protein 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AK155810, BE982271
    Consensus CDS
    CCDS28532.2
    UniProtKB/Swiss-Prot
    A0A3B2W707, Q3TA59, Q3U1Q1, Q91XD9, Q9D0L5
    UniProtKB/TrEMBL
    A0A9L6H220
    Related
    ENSMUSP00000026832.8, ENSMUST00000026832.14
    Conserved Domains (1) summary
    cl21464
    Location:59253
    cupin_like; Conserved domain found in cupin and related proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    26048017..26050817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)