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Ogfr opioid growth factor receptor [ Mus musculus (house mouse) ]

Gene ID: 72075, updated on 18-Apr-2024

Summary

Official Symbol
Ogfrprovided by MGI
Official Full Name
opioid growth factor receptorprovided by MGI
Primary source
MGI:MGI:1919325
See related
Ensembl:ENSMUSG00000049401 AllianceGenome:MGI:1919325
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010013E17Rik
Summary
Predicted to enable G protein-coupled opioid receptor activity. Predicted to act upstream of or within regulation of growth. Predicted to be located in cytoplasm; membrane; and nucleus. Is expressed in genitourinary system and metanephros. Orthologous to human OGFR (opioid growth factor receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 34.2), CNS E14 (RPKM 28.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
2 H4; 2 103.13 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180231200..180237630)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (180589407..180595837)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene neurotensin receptor 1 Neighboring gene predicted gene, 30144 Neighboring gene STARR-positive B cell enhancer ABC_E9543 Neighboring gene STARR-positive B cell enhancer ABC_E4530 Neighboring gene MRG/MORF4L binding protein Neighboring gene collagen, type IX, alpha 3 Neighboring gene transcription factor-like 5 (basic helix-loop-helix) Neighboring gene predicted gene, 54097 Neighboring gene death inducer-obliterator 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables opioid growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
opioid growth factor receptor
Names
zeta-type opioid receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031373.3NP_113550.3  opioid growth factor receptor

    See identical proteins and their annotated locations for NP_113550.3

    Status: VALIDATED

    Source sequence(s)
    AF303894, CJ144579, CO040942
    Consensus CDS
    CCDS17179.1
    UniProtKB/Swiss-Prot
    A2ACT6, Q99L33, Q99PG2
    UniProtKB/TrEMBL
    Q80UU6
    Related
    ENSMUSP00000029087.4, ENSMUST00000029087.4
    Conserved Domains (3) summary
    PHA03169
    Location:284548
    PHA03169; hypothetical protein; Provisional
    pfam04664
    Location:76283
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
    pfam15231
    Location:472620
    VCX_VCY; Variable charge X/Y family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    180231200..180237630
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319269.3XP_017174758.1  opioid growth factor receptor isoform X1

    UniProtKB/TrEMBL
    Q80UU6
    Conserved Domains (3) summary
    PTZ00449
    Location:414612
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03169
    Location:263527
    PHA03169; hypothetical protein; Provisional
    pfam04664
    Location:55262
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region
  2. XM_036162586.1XP_036018479.1  opioid growth factor receptor isoform X2

    UniProtKB/TrEMBL
    Q80UU6
    Conserved Domains (2) summary
    PTZ00449
    Location:349547
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam04664
    Location:38197
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region