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Slc38a10 solute carrier family 38, member 10 [ Mus musculus (house mouse) ]

Gene ID: 72055, updated on 12-May-2024

Summary

Official Symbol
Slc38a10provided by MGI
Official Full Name
solute carrier family 38, member 10provided by MGI
Primary source
MGI:MGI:1919305
See related
Ensembl:ENSMUSG00000061306 AllianceGenome:MGI:1919305
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810073N04Rik
Summary
Predicted to enable amino acid transmembrane transporter activity. Acts upstream of or within bone development. Predicted to be located in Golgi apparatus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SLC38A10 (solute carrier family 38 member 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in mammary gland adult (RPKM 28.3), subcutaneous fat pad adult (RPKM 28.2) and 28 other tissues See more
Orthologs
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Genomic context

See Slc38a10 in Genome Data Viewer
Location:
11 E2; 11 83.96 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (119994777..120042177, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (120103951..120151351, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E206 Neighboring gene TEPSIN, adaptor related protein complex 4 accessory protein Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:120011125-120011308 Neighboring gene STARR-positive B cell enhancer ABC_E382 Neighboring gene predicted gene 11769 Neighboring gene predicted gene, 39486 Neighboring gene STARR-seq mESC enhancer starr_31342 Neighboring gene predicted gene 9734 Neighboring gene regulator of early neurogenesis 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within amino acid transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within bone development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
solute carrier family 38 member 10
Names
amino acid transporter SLC38A10
novel amino acid transporter protein
putative sodium-coupled neutral amino acid transporter 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164798.1NP_001158270.1  solute carrier family 38 member 10 isoform 2

    See identical proteins and their annotated locations for NP_001158270.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK032245, BC088811, BY308707, BY630861
    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (2) summary
    COG0814
    Location:3397
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  2. NM_001164799.1NP_001158271.1  solute carrier family 38 member 10 isoform 3

    See identical proteins and their annotated locations for NP_001158271.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
    Source sequence(s)
    AK032245, AK159948, BY308707, BY630861
    Consensus CDS
    CCDS49000.1
    UniProtKB/TrEMBL
    J3QNE8
    Related
    ENSMUSP00000048675.8, ENSMUST00000045402.14
    Conserved Domains (2) summary
    COG0814
    Location:3397
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  3. NM_001164800.1NP_001158272.1  solute carrier family 38 member 10 isoform 4

    See identical proteins and their annotated locations for NP_001158272.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 4), compared to isoform 1.
    Source sequence(s)
    AK032245, BC082300, BY308707, BY630861
    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (2) summary
    COG0814
    Location:3397
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  4. NM_001164801.1NP_001158273.1  solute carrier family 38 member 10 isoform 5

    See identical proteins and their annotated locations for NP_001158273.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 5) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL807824, BC082300, BY308707
    Consensus CDS
    CCDS49002.1
    UniProtKB/Swiss-Prot
    Q5I012
    Related
    ENSMUSP00000057615.9, ENSMUST00000053692.9
    Conserved Domains (1) summary
    cl00456
    Location:6372
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  5. NM_001164802.1NP_001158274.1  solute carrier family 38 member 10 isoform 6

    See identical proteins and their annotated locations for NP_001158274.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 6) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AK007977, BY308707
    Consensus CDS
    CCDS49001.1
    UniProtKB/Swiss-Prot
    Q5I012
    Related
    ENSMUSP00000075989.7, ENSMUST00000076697.13
    Conserved Domains (1) summary
    cl00456
    Location:6378
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  6. NM_001361696.1NP_001348625.1  solute carrier family 38 member 10 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL807824
    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    pfam03157
    Location:5271010
    Glutenin_hmw; High molecular weight glutenin subunit
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    cl26511
    Location:407766
    Neuromodulin_N; Gap junction protein N-terminal region
  7. NM_001361697.1NP_001348626.1  solute carrier family 38 member 10 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AL807824
    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    cl25751
    Location:628887
    DUF4045; Domain of unknown function (DUF4045)
    cl26511
    Location:325685
    Neuromodulin_N; Gap junction protein N-terminal region
  8. NM_001361698.1NP_001348627.1  solute carrier family 38 member 10 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL807824
    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    cl00456
    Location:6293
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    cl25751
    Location:622882
    DUF4045; Domain of unknown function (DUF4045)
    cl26511
    Location:319682
    Neuromodulin_N; Gap junction protein N-terminal region
  9. NM_001361699.1NP_001348628.1  solute carrier family 38 member 10 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AL807824
    Conserved Domains (3) summary
    PTZ00121
    Location:182545
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:485745
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:8156
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  10. NM_024249.5NP_077211.4  solute carrier family 38 member 10 isoform 1

    See identical proteins and their annotated locations for NP_077211.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK032245, BC088811, BY308707, BY630861
    Consensus CDS
    CCDS25728.1
    UniProtKB/Swiss-Prot
    A2AMZ5, Q3TVW4, Q5I012, Q641M1, Q80ZZ4, Q8C1Y0, Q8CCR5, Q9D8J3
    UniProtKB/TrEMBL
    J3QNE8
    Related
    ENSMUSP00000099307.5, ENSMUST00000103018.11
    Conserved Domains (2) summary
    COG0814
    Location:3397
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    119994777..120042177 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246350.1XP_030102210.1  solute carrier family 38 member 10 isoform X8

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407724
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:667926
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  2. XM_017314782.1XP_017170271.1  solute carrier family 38 member 10 isoform X7

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (2) summary
    PTZ00121
    Location:407954
    PTZ00121; MAEBL; Provisional
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  3. XM_030246349.1XP_030102209.1  solute carrier family 38 member 10 isoform X6

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407758
    PTZ00121; MAEBL; Provisional
    pfam03157
    Location:552997
    Glutenin_hmw; High molecular weight glutenin subunit
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  4. XM_006534288.3XP_006534351.1  solute carrier family 38 member 10 isoform X5

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407759
    PTZ00121; MAEBL; Provisional
    pfam03157
    Location:552998
    Glutenin_hmw; High molecular weight glutenin subunit
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  5. XM_006534287.3XP_006534350.1  solute carrier family 38 member 10 isoform X4

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407767
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:709969
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  6. XM_006534285.3XP_006534348.1  solute carrier family 38 member 10 isoform X2

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407788
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:730990
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  7. XM_006534286.3XP_006534349.1  solute carrier family 38 member 10 isoform X3

    See identical proteins and their annotated locations for XP_006534349.1

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407788
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:731990
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  8. XM_030246352.2XP_030102212.1  solute carrier family 38 member 10 isoform X11

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:325688
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:628888
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  9. XM_006534284.3XP_006534347.1  solute carrier family 38 member 10 isoform X1

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:407789
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:731991
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6381
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  10. XM_036157009.1XP_036012902.1  solute carrier family 38 member 10 isoform X15

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:319674
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:614874
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6293
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  11. XM_006534291.3XP_006534354.1  solute carrier family 38 member 10 isoform X10

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:319701
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:643903
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:6293
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  12. XM_030246351.1XP_030102211.1  solute carrier family 38 member 10 isoform X9

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:325707
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:649909
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  13. XM_036157008.1XP_036012901.1  solute carrier family 38 member 10 isoform X14

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:325680
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:620880
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  14. XM_030246354.1XP_030102214.1  solute carrier family 38 member 10 isoform X13

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:325684
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:627886
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  15. XM_030246353.1XP_030102213.1  solute carrier family 38 member 10 isoform X12

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:325685
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:627887
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  16. XM_006534290.3XP_006534353.1  solute carrier family 38 member 10 isoform X9

    UniProtKB/TrEMBL
    J3QNE8
    Conserved Domains (3) summary
    PTZ00121
    Location:325707
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:649909
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl00456
    Location:2299
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain