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Mageb16 MAGE family member B16 [ Mus musculus (house mouse) ]

Gene ID: 71967, updated on 5-Mar-2024

Summary

Official Symbol
Mageb16provided by MGI
Official Full Name
MAGE family member B16provided by MGI
Primary source
MGI:MGI:1919217
See related
Ensembl:ENSMUSG00000046942 AllianceGenome:MGI:1919217
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410003J06Rik
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including brain; egg cylinder; heart; liver; and reproductive system. Orthologous to human MAGEB16 (MAGE family member B16). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta adult (RPKM 10.9) and testis adult (RPKM 3.3) See more
Orthologs
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Genomic context

See Mageb16 in Genome Data Viewer
Location:
X B; X 38.38 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (78666837..78715041, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (79623231..79671435, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47437 Neighboring gene cilia and flagella associated protein 47 Neighboring gene STARR-seq mESC enhancer starr_47438 Neighboring gene STARR-seq mESC enhancer starr_47439 Neighboring gene STARR-seq mESC enhancer starr_47441 Neighboring gene STARR-seq mESC enhancer starr_47442 Neighboring gene STARR-seq mESC enhancer starr_47443 Neighboring gene predicted gene, 17817 Neighboring gene STARR-seq mESC enhancer starr_47444 Neighboring gene hepatoma-derived growth factor pseudogene Neighboring gene STARR-seq mESC enhancer starr_47445 Neighboring gene STARR-seq mESC enhancer starr_47446 Neighboring gene STARR-seq mESC enhancer starr_47447 Neighboring gene STARR-seq mESC enhancer starr_47448 Neighboring gene STARR-seq mESC enhancer starr_47449 Neighboring gene ring finger protein pseudogene Neighboring gene prohibitin pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
melanoma-associated antigen B16
Names
MAGE-B16 antigen
Novel MAGE family protein
melanoma antigen family B, 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113734.1NP_001107206.1  melanoma-associated antigen B16

    See identical proteins and their annotated locations for NP_001107206.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
    Source sequence(s)
    AK010362, BY387905, CJ081836
    Consensus CDS
    CCDS53122.1
    UniProtKB/Swiss-Prot
    Q3TJP9, Q9CWV4
    Related
    ENSMUSP00000109649.4, ENSMUST00000114016.10
    Conserved Domains (1) summary
    pfam01454
    Location:217303
    MAGE; MAGE family
  2. NM_028025.1NP_082301.1  melanoma-associated antigen B16

    See identical proteins and their annotated locations for NP_082301.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
    Source sequence(s)
    AK010362, BY387905
    Consensus CDS
    CCDS53122.1
    UniProtKB/Swiss-Prot
    Q3TJP9, Q9CWV4
    Related
    ENSMUSP00000087292.4, ENSMUST00000052283.7
    Conserved Domains (1) summary
    pfam01454
    Location:217303
    MAGE; MAGE family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    78666837..78715041 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247683.3XP_011245985.1  melanoma-associated antigen B16 isoform X1

    See identical proteins and their annotated locations for XP_011245985.1

    UniProtKB/Swiss-Prot
    Q3TJP9, Q9CWV4
    Conserved Domains (1) summary
    pfam01454
    Location:217303
    MAGE; MAGE family