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Itfg1 integrin alpha FG-GAP repeat containing 1 [ Mus musculus (house mouse) ]

Gene ID: 71927, updated on 5-Mar-2024


Official Symbol
Itfg1provided by MGI
Official Full Name
integrin alpha FG-GAP repeat containing 1provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000031703 AllianceGenome:MGI:106419
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cda08; D8Wsu49e; 2310047C21Rik
Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in extraembryonic component; nervous system; and neural retina. Orthologous to human ITFG1 (integrin alpha FG-GAP repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in CNS E18 (RPKM 25.3), frontal lobe adult (RPKM 22.2) and 28 other tissues See more
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Genomic context

See Itfg1 in Genome Data Viewer
8 C3; 8 41.61 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (86444186..86567578, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (85717557..85840949, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53447 Neighboring gene neuropilin (NRP) and tolloid (TLL)-like 2 Neighboring gene microRNA 8109 Neighboring gene predicted gene, 39214 Neighboring gene STARR-seq mESC enhancer starr_22171 Neighboring gene ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E, pseudogene 1 Neighboring gene potassium channel tetramerisation domain containing 7 pseudogene Neighboring gene phosphorylase kinase beta Neighboring gene STARR-seq mESC enhancer starr_22173 Neighboring gene STARR-seq mESC enhancer starr_22174 Neighboring gene kallikrein related-peptidase 7 (chymotryptic, stratum corneum) pseudogene

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info

General protein information

Preferred Names
T-cell immunomodulatory protein
integrin-alpha FG-GAP repeat-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028007.3NP_082283.2  T-cell immunomodulatory protein precursor

    See identical proteins and their annotated locations for NP_082283.2

    Status: VALIDATED

    Source sequence(s)
    AK132242, AK141948, AV257002, BP765330, DN175510
    Consensus CDS
    E9QQ11, Q99KW9, Q9D6X1
    ENSMUSP00000034140.8, ENSMUST00000034140.9
    Conserved Domains (1) summary
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000074.7 Reference GRCm39 C57BL/6J

    86444186..86567578 complement
    GenBank, FASTA, Sequence Viewer (Graphics)