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Jsrp1 junctional sarcoplasmic reticulum protein 1 [ Mus musculus (house mouse) ]

Gene ID: 71912, updated on 4-May-2024

Summary

Official Symbol
Jsrp1provided by MGI
Official Full Name
junctional sarcoplasmic reticulum protein 1provided by MGI
Primary source
MGI:MGI:1916700
See related
Ensembl:ENSMUSG00000020216 AllianceGenome:MGI:1916700
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
JP45; JP-45; 2300003C06Rik; 2310032K21Rik
Summary
Acts upstream of or within protein localization to membrane and regulation of ryanodine-sensitive calcium-release channel activity. Located in sarcoplasmic reticulum. Is expressed in skeletal muscle and tongue. Orthologous to human JSRP1 (junctional sarcoplasmic reticulum protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in mammary gland adult (RPKM 5.5), ovary adult (RPKM 5.4) and 11 other tissues See more
Orthologs
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Genomic context

See Jsrp1 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80644330..80649359, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80808494..80813741, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene splicing factor 3a, subunit 2 Neighboring gene Amh promoter region Neighboring gene anti-Mullerian hormone Neighboring gene STARR-seq mESC enhancer starr_27299 Neighboring gene STARR-positive B cell enhancer ABC_E369 Neighboring gene ornithine decarboxylase antizyme 1 Neighboring gene microRNA 1982 Neighboring gene leucine rich repeat and Ig domain containing 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Pathways from PubChem

General protein information

Preferred Names
junctional sarcoplasmic reticulum protein 1
Names
junctional-face membrane protein of 45 kDa homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028001.3NP_082277.2  junctional sarcoplasmic reticulum protein 1

    See identical proteins and their annotated locations for NP_082277.2

    Status: VALIDATED

    Source sequence(s)
    AC166937
    Consensus CDS
    CCDS24034.2
    UniProtKB/Swiss-Prot
    Q3MI48, Q9D755
    UniProtKB/TrEMBL
    M0QW57
    Related
    ENSMUSP00000137666.2, ENSMUST00000181039.8
    Conserved Domains (2) summary
    PRK14954
    Location:160276
    PRK14954; DNA polymerase III subunits gamma and tau; Provisional
    pfam15312
    Location:119178
    JSRP; Junctional sarcoplasmic reticulum protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    80644330..80649359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156028.1XP_036011921.1  junctional sarcoplasmic reticulum protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q3MI48, Q9D755
    UniProtKB/TrEMBL
    M0QW57
    Conserved Domains (2) summary
    PRK14954
    Location:160276
    PRK14954; DNA polymerase III subunits gamma and tau; Provisional
    pfam15312
    Location:119178
    JSRP; Junctional sarcoplasmic reticulum protein