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Apmap adipocyte plasma membrane associated protein [ Mus musculus (house mouse) ]

Gene ID: 71881, updated on 12-May-2024

Summary

Official Symbol
Apmapprovided by MGI
Official Full Name
adipocyte plasma membrane associated proteinprovided by MGI
Primary source
MGI:MGI:1919131
See related
Ensembl:ENSMUSG00000033096 AllianceGenome:MGI:1919131
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310001A20Rik
Summary
Predicted to enable arylesterase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cell surface and membrane. Is expressed in olfactory epithelium. Orthologous to human APMAP (adipocyte plasma membrane associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 26.0), subcutaneous fat pad adult (RPKM 25.0) and 28 other tissues See more
Orthologs
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Genomic context

See Apmap in Genome Data Viewer
Location:
2 G3; 2 74.68 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (150425000..150450487, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (150583080..150608567, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ankyrin and armadillo repeat containing pseudogene Neighboring gene STARR-seq mESC enhancer starr_06007 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:150404413-150404596 Neighboring gene cystatin F (leukocystatin) Neighboring gene STARR-positive B cell enhancer ABC_E2647 Neighboring gene predicted gene, 52532 Neighboring gene acyl-CoA synthetase short-chain family member 1 Neighboring gene STARR-seq mESC enhancer starr_06012 Neighboring gene RIKEN cDNA E130215H24 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables arylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables arylesterase activity ISO
Inferred from Sequence Orthology
more info
 
enables strictosidine synthase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
adipocyte plasma membrane-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356491.1NP_001343420.1  adipocyte plasma membrane-associated protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AL845174
    Conserved Domains (2) summary
    COG3386
    Location:1243
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cl22863
    Location:124211
    Str_synth; Strictosidine synthase
  2. NM_001356492.1NP_001343421.1  adipocyte plasma membrane-associated protein isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and uses an alternate splice junction compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AL845174
    Conserved Domains (1) summary
    cl22863
    Location:592
    Str_synth; Strictosidine synthase
  3. NM_027977.3NP_082253.1  adipocyte plasma membrane-associated protein isoform 1

    See identical proteins and their annotated locations for NP_082253.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AK009057, BY230335
    Consensus CDS
    CCDS16858.1
    UniProtKB/Swiss-Prot
    A2AQX3, Q3U4F4, Q9D7N9
    Related
    ENSMUSP00000040840.7, ENSMUST00000046399.7
    Conserved Domains (4) summary
    COG3386
    Location:72319
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cd05819
    Location:101136
    NHL; NHL repeat [structural motif]
    cl18310
    Location:95283
    NHL; NHL repeat unit of beta-propeller proteins
    cl22863
    Location:200287
    Str_synth; Strictosidine synthase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    150425000..150450487 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500198.4XP_006500261.1  adipocyte plasma membrane-associated protein isoform X1

    Conserved Domains (2) summary
    COG3386
    Location:33280
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cl22863
    Location:161248
    Str_synth; Strictosidine synthase
  2. XM_036162580.1XP_036018473.1  adipocyte plasma membrane-associated protein isoform X2

    Conserved Domains (1) summary
    cl22863
    Location:592
    Str_synth; Strictosidine synthase